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    ARHGEF10L Rho guanine nucleotide exchange factor 10 like [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701164, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGEF10Lprovided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 10 likeprovided by VGNC
    Primary source
    VGNC:VGNC:69908
    See related
    Ensembl:ENSMMUG00000010849
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF10L in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (207049318..207227740, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (16243960..16423462)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene immunoglobin superfamily member 21 Neighboring gene actin like 8 Neighboring gene uncharacterized LOC114673995 Neighboring gene regulator of chromosome condensation 2 Neighboring gene peptidyl arginine deiminase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SREBP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 10-like protein
    Names
    Rho guanine nucleotide exchange factor (GEF) 10-like

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      207049318..207227740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001089828.4 → XP_001089828.2  rho guanine nucleotide exchange factor 10-like protein isoform X11

      UniProtKB/TrEMBL
      F7G3F5, I0FT05
      Related
      ENSMMUP00000014221.4, ENSMMUT00000015177.4
      Conserved Domains (2) summary
      smart00325
      Location:279 → 461
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    2. XM_001089707.4 → XP_001089707.2  rho guanine nucleotide exchange factor 10-like protein isoform X10

      UniProtKB/TrEMBL
      F7G3F1, F7G3F5
      Related
      ENSMMUP00000014222.4, ENSMMUT00000015178.4
      Conserved Domains (2) summary
      smart00325
      Location:279 → 461
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    3. XM_015125089.2 → XP_014980575.2  rho guanine nucleotide exchange factor 10-like protein isoform X12

      UniProtKB/TrEMBL
      A0A5F7ZAY6, F7G3F5
      Related
      ENSMMUP00000062726.1, ENSMMUT00000083537.1
      Conserved Domains (1) summary
      cd00160
      Location:95 → 279
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    4. XM_028838907.1 → XP_028694740.1  rho guanine nucleotide exchange factor 10-like protein isoform X2

      UniProtKB/TrEMBL
      G7MH60
      Related
      ENSMMUP00000069981.1, ENSMMUT00000085171.1
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:318 → 502
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    5. XM_028838896.1 → XP_028694729.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:319 → 503
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    6. XM_028838891.1 → XP_028694724.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:319 → 503
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    7. XM_028838899.1 → XP_028694732.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:319 → 503
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    8. XM_028838902.1 → XP_028694735.1  rho guanine nucleotide exchange factor 10-like protein isoform X2

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:318 → 502
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    9. XM_028838935.1 → XP_028694768.1  rho guanine nucleotide exchange factor 10-like protein isoform X8

      UniProtKB/TrEMBL
      F7G3F5
      Conserved Domains (2) summary
      smart00325
      Location:283 → 465
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    10. XM_028838921.1 → XP_028694754.1  rho guanine nucleotide exchange factor 10-like protein isoform X5

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:319 → 503
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    11. XM_015124833.2 → XP_014980319.2  rho guanine nucleotide exchange factor 10-like protein isoform X7

      UniProtKB/TrEMBL
      A0A5F7ZPL8, G7MH60
      Related
      ENSMMUP00000067126.1, ENSMMUT00000106163.1
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:315 → 499
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    12. XM_015124905.2 → XP_014980391.2  rho guanine nucleotide exchange factor 10-like protein isoform X9

      UniProtKB/TrEMBL
      F7G3F5
      Conserved Domains (2) summary
      smart00325
      Location:280 → 462
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    13. XM_015124800.2 → XP_014980286.2  rho guanine nucleotide exchange factor 10-like protein isoform X6

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:316 → 500
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    14. XM_015124528.2 → XP_014980014.2  rho guanine nucleotide exchange factor 10-like protein isoform X3

      UniProtKB/TrEMBL
      G7MH60
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 167
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:316 → 500
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    15. XM_028838912.1 → XP_028694745.1  rho guanine nucleotide exchange factor 10-like protein isoform X4

      UniProtKB/TrEMBL
      F7G3F9, G7MH60
      Related
      ENSMMUP00000014220.4, ENSMMUT00000015176.4
      Conserved Domains (2) summary
      PRK07764
      Location:2 → 147
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd00160
      Location:315 → 499
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    16. XM_028838964.1 → XP_028694797.1  rho guanine nucleotide exchange factor 10-like protein isoform X14

      UniProtKB/TrEMBL
      F7G3F5
      Conserved Domains (1) summary
      cd00160
      Location:78 → 262
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    17. XM_015125156.2 → XP_014980642.2  rho guanine nucleotide exchange factor 10-like protein isoform X13

      UniProtKB/TrEMBL
      F7G3F5
      Conserved Domains (1) summary
      cd00160
      Location:95 → 279
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    Nucleotide Protein
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