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    DDR2 discoidin domain receptor tyrosine kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720124, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DDR2provided by VGNC
    Official Full Name
    discoidin domain receptor tyrosine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:71758
    Locus tag
    EGK_01556
    See related
    Ensembl:ENSMMUG00000009330
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DDR2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (88163360..88326607, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (137423894..137585523)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 3-keto-steroid reductase-like Neighboring gene 3-keto-steroid reductase Neighboring gene UDP-N-acetylglucosamine pyrophosphorylase 1 Neighboring gene U2AF homology motif kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables collagen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase collagen receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    discoidin domain-containing receptor 2
    XP_014969572.1
    XP_014969574.1
    XP_028682490.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      88163360..88326607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015114088.2 → XP_014969574.1  discoidin domain-containing receptor 2 isoform X1

      UniProtKB/TrEMBL
      A0A5S6RBC1, A0A8J8YII3, F7HJQ2, G7MEB8, H9F8B9
      Related
      ENSMMUP00000012220.4, ENSMMUT00000013038.4
      Conserved Domains (2) summary
      cd00057
      Location:32 → 184
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd05095
      Location:557 → 851
      PTKc_DDR2; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 2

    2. XM_015114086.2 → XP_014969572.1  discoidin domain-containing receptor 2 isoform X1

      UniProtKB/TrEMBL
      A0A5S6RBC1, A0A8J8YII3, F7HJQ2, G7MEB8, H9F8B9
      Conserved Domains (2) summary
      cd00057
      Location:32 → 184
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd05095
      Location:557 → 851
      PTKc_DDR2; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 2

    3. XM_028826657.1 → XP_028682490.1  discoidin domain-containing receptor 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A058, H9F8B9
      Related
      ENSMMUP00000071300.1, ENSMMUT00000095535.1
      Conserved Domains (2) summary
      cd00057
      Location:1 → 149
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd05095
      Location:522 → 816
      PTKc_DDR2; Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 2
    Nucleotide Protein
    Heading Accession and Version

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