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    ifitm1 interferon induced transmembrane protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100003209, updated on 9-Dec-2024

    Summary

    Official Symbol
    ifitm1provided by ZNC
    Official Full Name
    interferon induced transmembrane protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-259
    See related
    Ensembl:ENSDARG00000093303 AllianceGenome:ZFIN:ZDB-GENE-060526-259
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-226m8.7
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including kidney; liver; post-vent region; reproductive system; and tail bud. Human ortholog(s) of this gene implicated in COVID-19; adenosquamous gallbladder carcinoma; and gallbladder adenocarcinoma. Orthologous to human IFITM1 (interferon induced transmembrane protein 1); IFITM2 (interferon induced transmembrane protein 2); and IFITM3 (interferon induced transmembrane protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ifitm1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33258289..33259079, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32658136..32658926, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene KN motif and ankyrin repeat domains 1b Neighboring gene protein kinase, AMP-activated, alpha 1 catalytic subunit Neighboring gene kynurenine aminotransferase 1 Neighboring gene surfeit 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    interferon-induced transmembrane protein 1
    Names
    interferon induced transmembrane protein 1 (9-27)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110287.1NP_001103757.1  interferon-induced transmembrane protein 1

      See identical proteins and their annotated locations for NP_001103757.1

      Status: PREDICTED

      Source sequence(s)
      CR382323
      UniProtKB/TrEMBL
      A5WUL9, E9K819
      Related
      ENSDARP00000121961.1, ENSDART00000132223.2
      Conserved Domains (1) summary
      pfam04505
      Location:2597
      CD225; Interferon-induced transmembrane protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      33258289..33259079 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)