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    tfdp2 transcription factor Dp-2 [ Danio rerio (zebrafish) ]

    Gene ID: 338204, updated on 15-Dec-2024

    Summary

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    Official Symbol
    tfdp2provided by ZNC
    Official Full Name
    transcription factor Dp-2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030219-104
    See related
    Ensembl:ENSDARG00000042835 AllianceGenome:ZFIN:ZDB-GENE-030219-104
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    id:ibd2511; wu:fb94f09; zgc:110490
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription and regulation of cell cycle. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain; spinal cord; and telencephalon. Orthologous to human TFDP2 (transcription factor Dp-2). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See tfdp2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (4421801..4491822, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (4430654..4500675, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene endothelin converting enzyme 2b Neighboring gene uncharacterized LOC103908795 Neighboring gene ATPase Na+/K+ transporting subunit beta 3b Neighboring gene uncharacterized LOC137487714 Neighboring gene uncharacterized LOC103908797 Neighboring gene ring finger and FYVE-like domain containing E3 ubiquitin protein ligase Neighboring gene eukaryotic translation initiation factor 4h

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b. Zhao S, et al. Cell Death Discov, 2024 Apr 18. PMID 38637503, Free PMC Article
    2. Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish. Yang YJ, et al. Genetics, 2017 Apr. PMID 28193729, Free PMC Article
    3. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
    4. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor Dp-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198208.1 → NP_937851.1  transcription factor Dp-2

      See identical proteins and their annotated locations for NP_937851.1

      Status: PROVISIONAL

      Source sequence(s)
      AY391466
      UniProtKB/TrEMBL
      Q6TNQ1
      Related
      ENSDARP00000129833.1, ENSDART00000155619.3
      Conserved Domains (3) summary
      cd14458
      Location:221 → 267
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:136 → 216
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:223 → 362
      DP; Transcription factor DP

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      4421801..4491822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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