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    Traf4 TNF receptor associated factor 4 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100762863, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Traf4
    Gene description
    TNF receptor associated factor 4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Orthologs
    human mouse all
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    Genomic context

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    See Traf4 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003616155.1 (114984..120754)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (91549114..91556299, complement)

    NW_003616155.1Genomic Context describing neighboring genes Neighboring gene TLC domain containing 1 Neighboring gene NIMA related kinase 8 Neighboring gene family with sequence similarity 222 member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of NF-kappaB-inducing kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TNF receptor-associated factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003616155.1 Reference CriGri_1.0 Primary Assembly

      Range
      114984..120754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003513832.5 → XP_003513880.1  TNF receptor-associated factor 4 isoform X1

      See identical proteins and their annotated locations for XP_003513880.1

      UniProtKB/TrEMBL
      A0A8C2M7M3, G3IGI3
      Conserved Domains (3) summary
      cd00162
      Location:18 → 55
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd03781
      Location:308 → 463
      MATH_TRAF4; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF4 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF4, including the Drosophila protein DTRAF1. TRAF molecules serve as adapter ...
      pfam02176
      Location:210 → 269
      zf-TRAF; TRAF-type zinc finger

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NC_048600.1 Alternate CriGri-PICRH-1.0

      Range
      91549114..91556299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027426114.1 → XP_027281915.1  TNF receptor-associated factor 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C2M7M3, A0A9J7GH12
    Nucleotide Protein Strain
    Heading Accession and Version

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