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    C2H2 and C2HC zinc fingers superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841383, updated on 18-Sep-2024

    Summary

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    Official Full Name
    C2H2 and C2HC zinc fingers superfamily protein
    Primary source
    TAIR:AT1G49590
    Locus tag
    AT1G49590
    See related
    Araport:AT1G49590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14J22.17; F14J22_17; Zinc-finger and OCRE domain-containing Protein 1; ZOP1
    Summary
    Encodes a novel nucleic acid-binding protein that is required for both RdDM (RNA-directed DNA methylation) and pre-mRNA splicing.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (18354744..18356733)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Peroxidase superfamily protein Neighboring gene Calcium-dependent protein kinase (CDPK) family protein Neighboring gene RNA-binding protein 47A Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The splicing machinery promotes RNA-directed DNA methylation and transcriptional silencing in Arabidopsis. Zhang CJ, et al. EMBO J, 2013 Apr 17. PMID 23524848, Free PMC Article
    2. The Splicing Factor PRP31 Is Involved in Transcriptional Gene Silencing and Stress Response in Arabidopsis. Du JL, et al. Mol Plant, 2015 Jul. PMID 25684655
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001160940.2
    NM_001333391.1
    NM_103847.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables double-stranded RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within gene silencing by siRNA-directed DNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Cajal body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    C2H2 and C2HC zinc fingers superfamily protein
    NP_001154412.1
    • C2H2 and C2HC zinc fingers superfamily protein; FUNCTIONS IN: zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, U1-C type (InterPro:IPR013085), Zinc finger, U1-type (InterPro:IPR003604), Zinc finger, C2H2-type matrin (InterPro:IPR000690); Has 251 Blast hits to 251 proteins in 132 species: Archae - 0; Bacteria - 0; Metazoa - 115; Fungi - 52; Plants - 43; Viruses - 0; Other Eukaryotes - 41 (source: NCBI BLink).
    NP_001319183.1
    • C2H2 and C2HC zinc fingers superfamily protein; FUNCTIONS IN: zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, U1-C type (InterPro:IPR013085), Zinc finger, U1-type (InterPro:IPR003604), Zinc finger, C2H2-type matrin (InterPro:IPR000690).
    NP_175382.1
    • C2H2 and C2HC zinc fingers superfamily protein; FUNCTIONS IN: zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, U1-C type (InterPro:IPR013085), Zinc finger, C2H2-type matrin (InterPro:IPR000690); Has 448 Blast hits to 444 proteins in 139 species: Archae - 0; Bacteria - 0; Metazoa - 237; Fungi - 54; Plants - 111; Viruses - 0; Other Eukaryotes - 46 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18354744..18356733
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333391.1 → NP_001319183.1  C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W615, F4I3B2

    2. NM_001160940.2 → NP_001154412.1  C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154412.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4I3B1

    3. NM_103847.5 → NP_175382.1  C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175382.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7XA66, Q94AV7, Q9FX87
      UniProtKB/TrEMBL
      A0A178W5A8, A0A5S9WN93, A0A654EGY9
      Conserved Domains (2) summary
      cd16165
      Location:93 → 142
      OCRE_ZOP1_plant; OCRE domain found in Zinc-finger and OCRE domain-containing Protein 1 (ZOP1) and similar proteins found in plant
      cl22907
      Location:8 → 42
      zf-U1; U1 zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7XA66.1

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