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    mtx2.L metaxin 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 407750, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mtx2.L
    Official Full Name
    metaxin 2 L homeolog
    Primary source
    Xenbase:XB-GENE-943948
    Locus tag
    XELAEV_18044733mg
    See related
    EnsemblRapid:ENSXLAG00005024537 AllianceGenome:Xenbase:XB-GENE-943948
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    mtx2; xmtx2
    Summary
    Predicted to act upstream of or within mitochondrion organization and protein transport. Predicted to be located in mitochondrial outer membrane. Predicted to be part of SAM complex. Orthologous to human MTX2 (metaxin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See mtx2.L in Genome Data Viewer
    Location:
    chromosome: 9_10L
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (78391442..78441429, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (67882886..67933356, complement)

    Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene NFE2 like bZIP transcription factor 2 L homeolog Neighboring gene heterogeneous nuclear ribonucleoprotein A3 L homeolog Neighboring gene uncharacterized LOC108701380 Neighboring gene homeobox D1 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the cDNA and amino acid sequences of Xenopus Metaxin 3, and relationship to Xenopus Metaxins 1 and 2. Adolph KW. DNA Seq, 2005 Aug. PMID 16147884
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SAM complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    metaxin 2 L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001091003.1 → NP_001084472.1  metaxin 2 L homeolog

      See identical proteins and their annotated locations for NP_001084472.1

      Status: PROVISIONAL

      Source sequence(s)
      AY553052
      UniProtKB/TrEMBL
      Q6GPN0, Q6Q8B0
      Related
      ENSXLAP00005073032.1, ENSXLAT00005074596.1
      Conserved Domains (3) summary
      cd03211
      Location:125 → 250
      GST_C_Metaxin2; C-terminal, alpha helical domain of Metaxin 2
      COG0625
      Location:34 → 252
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03079
      Location:22 → 95
      GST_N_Metaxin2; GST_N family, Metaxin subfamily, Metaxin 2; a metaxin 1 binding protein identified through a yeast two-hybrid system using metaxin 1 as the bait. Metaxin 2 shares sequence similarity with metaxin 1 but does not contain a C-terminal mitochondrial outer ...

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      78391442..78441429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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