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    slc7a5.L solute carrier family 7 member 5 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398978, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc7a5.L
    Official Full Name
    solute carrier family 7 member 5 L homeolog
    Primary source
    Xenbase:XB-GENE-6254908
    Locus tag
    XELAEV_18022696mg
    See related
    EnsemblRapid:ENSXLAG00005031200 AllianceGenome:Xenbase:XB-GENE-6254908
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    e16; cd98; lat1; 4f2lc; LAT-1; asur4; mpe16; slc7a5; slc7a5b; slc7a5-a; slc7a5-b; AmAt-L-lc
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Predicted to act upstream of or within amino acid transmembrane transport and neutral amino acid transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; hepatocellular carcinoma; and lung squamous cell carcinoma. Orthologous to human SLC7A5 (solute carrier family 7 member 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slc7a5.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (59810934..59846794, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (54607254..54642966, complement)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene junctophilin 3 L homeolog Neighboring gene kelch domain containing 4 L homeolog Neighboring gene carbonic anhydrase VB, mitochondrial L homeolog Neighboring gene BTG3 associated nuclear protein L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Mastroberardino L, et al. Nature, 1998 Sep 17. PMID 9751058
    2. Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance. Torrents D, et al. J Biol Chem, 1998 Dec 4. PMID 9829974
    3. Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia. Spindler B, et al. Pflugers Arch, 1997 Jul. PMID 9178633
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neutral amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 7, member 5 b
    Names
    L amino acid transporter-1
    amino acid transporter chain asur4
    solute carrier family 7 (amino acid transporter light chain, L system), member 5 L homeolog
    solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001090065.1 → NP_001083534.1  solute carrier family 7, member 5 b

      See identical proteins and their annotated locations for NP_001083534.1

      Status: PROVISIONAL

      Source sequence(s)
      BC060751
      UniProtKB/TrEMBL
      A0A974HNY8, O57439, Q6P9I4
      Related
      ENSXLAP00005093574.1, ENSXLAT00005095268.1
      Conserved Domains (1) summary
      TIGR00911
      Location:1 → 506
      2A0308; L-type amino acid transporter

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      59810934..59846794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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