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    aip aryl hydrocarbon receptor interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 334795, updated on 9-Dec-2024

    Summary

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    Official Symbol
    aipprovided by ZNC
    Official Full Name
    aryl hydrocarbon receptor interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6735
    See related
    Ensembl:ENSDARG00000104437 AllianceGenome:ZFIN:ZDB-GENE-030131-6735
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fa03h10; zgc:101101
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in pituitary adenoma 1. Orthologous to human AIP (aryl hydrocarbon receptor interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See aip in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (39995074..40009755)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39276954..39291682)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene storkhead box 2a Neighboring gene superoxide dismutase 3, extracellular b Neighboring gene inhibitor of growth family, member 2 Neighboring gene cyclin dependent kinase 2 associated protein 2 Neighboring gene leucine-rich repeat LGI family, member 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A temporal high-resolution investigation of the Ah-receptor pathway during early development of zebrafish (Danio rerio). Meyer-Alert H, et al. Aquat Toxicol, 2018 Nov. PMID 30245344
    2. Toxic effects and transcriptome analyses of zebrafish (Danio rerio) larvae exposed to benzophenones. Meng Q, et al. Environ Pollut, 2020 Oct. PMID 32497821
    3. Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae. Liu C, et al. Aquat Toxicol, 2013 Mar 15. PMID 23306105
    4. Integrated in silico and in vivo approaches to investigate effects of BDE-99 mediated by the nuclear receptors on developing zebrafish. Zhang L, et al. Environ Toxicol Chem, 2018 Mar. PMID 29027256
    5. Differential modulation of expression of nuclear receptor mediated genes by tris(2-butoxyethyl) phosphate (TBOEP) on early life stages of zebrafish (Danio rerio). Ma Z, et al. Aquat Toxicol, 2015 Dec. PMID 26562049

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC101101

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AH receptor-interacting protein
    NP_999877.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214712.1 → NP_999877.1  AH receptor-interacting protein

      See identical proteins and their annotated locations for NP_999877.1

      Status: PROVISIONAL

      Source sequence(s)
      AF274877
      UniProtKB/TrEMBL
      Q90ZC5
      Related
      ENSDARP00000140632.1, ENSDART00000166251.2
      Conserved Domains (3) summary
      sd00006
      Location:184 → 226
      TPR; TPR repeat [structural motif]
      pfam00254
      Location:30 → 91
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase
      pfam13414
      Location:245 → 297
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      39995074..40009755
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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