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    Pseudouridine synthase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843937, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Pseudouridine synthase family protein
    Primary source
    TAIR:AT1G76050
    Locus tag
    AT1G76050
    See related
    Araport:AT1G76050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T4O12.210; T4O12_210
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (28540784..28543227)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ATPase, V1 complex, subunit B protein Neighboring gene calcium-dependent protein kinase 29 Neighboring gene LYR family of Fe/S cluster biogenesis protein Neighboring gene LYR family of Fe/S cluster biogenesis protein Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in SUPPRESSOR OF VARIEGATION1, a factor required for normal chloroplast translation, suppress var2-mediated leaf variegation in Arabidopsis. Yu F, et al. Plant Cell, 2008 Jul. PMID 18599582, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_106254.3
    NM_202422.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables pseudouridine synthase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Pseudouridine synthase family protein
    NP_177732.2
    • Pseudouridine synthase family protein; FUNCTIONS IN: pseudouridine synthase activity; INVOLVED IN: pseudouridine synthesis, RNA modification; LOCATED IN: chloroplast; EXPRESSED IN: shoot, leaf lamina base, stem, embryo, leaf whorl; EXPRESSED DURING: D bilateral stage; CONTAINS InterPro DOMAIN/s: Pseudouridine synthase, catalytic domain (InterPro:IPR020103), Pseudouridine synthase, RsuA and RluB/C/D/E/F (InterPro:IPR006145), Pseudouridine synthase, RluC/RluD, conserved site (InterPro:IPR006224), RNA-binding S4 (InterPro:IPR002942); Has 15192 Blast hits to 15192 proteins in 2580 species: Archae - 12; Bacteria - 11504; Metazoa - 97; Fungi - 82; Plants - 90; Viruses - 0; Other Eukaryotes - 3407 (source: NCBI BLink).
    NP_974151.1
    • Pseudouridine synthase family protein; FUNCTIONS IN: pseudouridine synthase activity; INVOLVED IN: pseudouridine synthesis, RNA modification; LOCATED IN: chloroplast; EXPRESSED IN: shoot, leaf lamina base, stem, embryo, leaf whorl; EXPRESSED DURING: D bilateral stage; CONTAINS InterPro DOMAIN/s: Pseudouridine synthase, RluC/RluD (InterPro:IPR006225), Pseudouridine synthase, catalytic domain (InterPro:IPR020103), Pseudouridine synthase, RsuA and RluB/C/D/E/F (InterPro:IPR006145), Pseudouridine synthase, RluC/RluD, conserved site (InterPro:IPR006224), RNA-binding S4 (InterPro:IPR002942); BEST Arabidopsis thaliana protein match is: Pseudouridine synthase family protein (TAIR:AT3G19440.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28540784..28543227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202422.3 → NP_974151.1  Pseudouridine synthase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974151.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3ECD0, Q8GY94
      UniProtKB/TrEMBL
      A0A178WC45, A0A654F028
      Conserved Domains (3) summary
      cd02869
      Location:157 → 399
      PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
      COG0564
      Location:73 → 415
      RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]
      cd00165
      Location:82 → 161
      S4; S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized ...

    2. NM_106254.3 → NP_177732.2  Pseudouridine synthase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177732.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3ECD0
      Conserved Domains (3) summary
      cd02869
      Location:157 → 298
      PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
      COG0564
      Location:73 → 301
      RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]
      cd00165
      Location:82 → 161
      S4; S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ECD0.1

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