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    MYLIP myosin regulatory light chain interacting protein [ Vulpes vulpes (red fox) ]

    Gene ID: 112920528, updated on 15-Mar-2024

    Summary

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    Gene symbol
    MYLIP
    Gene description
    myosin regulatory light chain interacting protein
    See related
    Ensembl:ENSVVUG00000003403
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Vulpes vulpes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
    Orthologs
    human mouse all
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    Genomic context

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    See MYLIP in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356465.1 (9082074..9102438, complement)

    NW_020356465.1Genomic Context describing neighboring genes Neighboring gene ataxin 1 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene guanosine monophosphate reductase Neighboring gene uncharacterized LOC112920529 Neighboring gene dystrobrevin binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020356465 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytoskeletal protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MYLIP

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference VulVul2.2 Primary Assembly

    Genomic

    1. NW_020356465.1 Reference VulVul2.2 Primary Assembly

      Range
      9082074..9102438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025999334.1 → XP_025855119.1  E3 ubiquitin-protein ligase MYLIP

      UniProtKB/TrEMBL
      A0A3Q7S742
      Related
      ENSVVUP00000004317.1, ENSVVUT00000005898.1
      Conserved Domains (4) summary
      smart00295
      Location:5 → 190
      B41; Band 4.1 homologues
      cd13195
      Location:185 → 295
      FERM_C_MYLIP_IDOL; FERM domain C-lobe of E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP; also called inducible degrader of the LDL receptor, IDOL)
      cd16523
      Location:386 → 423
      RING-HC_MYLIP; RING finger, HC subclass, found in myosin regulatory light chain interacting protein (MYLIP) and similar proteins
      cd17104
      Location:1 → 81
      FERM_F1_MYLIP; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in E3 ubiquitin-protein ligase MYLIP and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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