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    Cpr Cytochrome P450 reductase [ Apis florea (little honeybee) ]

    Gene ID: 100867807, updated on 9-Nov-2024

    Summary

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    Gene symbol
    Cpr
    Gene description
    Cytochrome P450 reductase
    See related
    EnsemblRapid:LOC100867807
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Apis florea
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Apis
    Orthologs
    fruit fly honey bee all
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    Genomic context

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    See Cpr in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    102 current Aflo_1.1 (GCF_000184785.3) Unplaced Scaffold NW_003790299.1 (214379..232536)

    NW_003790299.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L23A Neighboring gene RAS oncogene family member RabX5 Neighboring gene rootletin-like Neighboring gene SET domain containing 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_003790299 Unplaced Scaffold Reference Aflo_1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genes involved in convergent evolution of eusociality in bees. Woodard SH, et al. Proc Natl Acad Sci U S A, 2011 May 3. PMID 21482769, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADPH-hemoprotein reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH--cytochrome P450 reductase
    NP_001351669.1
    NP_001351670.1
    NP_001351672.1
    XP_031772135.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364740.1 → NP_001351669.1  NADPH--cytochrome P450 reductase isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer/longest* isoform (1).
      Source sequence(s)
      AEKZ01005614
      Related
      NP_001351669.1, NM_001364740.1
      Conserved Domains (2) summary
      cd06204
      Location:295 → 692
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      pfam00258
      Location:100 → 237
      Flavodoxin_1; Flavodoxin

    2. NM_001364741.1 → NP_001351670.1  NADPH--cytochrome P450 reductase isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 2.
      Source sequence(s)
      AEKZ01005614
      Related
      NP_001351670.1, NM_001364741.1
      Conserved Domains (2) summary
      cd06204
      Location:280 → 677
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      pfam00258
      Location:85 → 222
      Flavodoxin_1; Flavodoxin

    3. NM_001364743.1 → NP_001351672.1  NADPH--cytochrome P450 reductase isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2,
      Source sequence(s)
      AEKZ01005614
      Related
      NP_001351672.1, NM_001364743.1
      Conserved Domains (2) summary
      cd06204
      Location:280 → 677
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      pfam00258
      Location:85 → 222
      Flavodoxin_1; Flavodoxin

    RefSeqs of Annotated Genomes: Apis florea Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Aflo_1.1 Primary Assembly

    Genomic

    1. NW_003790299.1 Reference Aflo_1.1 Primary Assembly

      Range
      214379..232536
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031916275.1 → XP_031772135.1  NADPH--cytochrome P450 reductase isoform X1

      Related
      XP_031772135.1, XM_031916275.1
      Conserved Domains (2) summary
      cd06204
      Location:145 → 542
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      pfam00258
      Location:36 → 87
      Flavodoxin_1
    Nucleotide Protein
    Heading Accession and Version

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