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    PRF5 profilin 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816496, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRF5
    Official Full Name
    profilin 5
    Primary source
    TAIR:AT2G19770
    Locus tag
    AT2G19770
    See related
    Araport:AT2G19770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6F22.20; F6F22_20; profilin 5
    Summary
    Encodes profilin 5, originally named profilin 4 (PRO4/PFN4). Low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton. Pollen-specific plant profilin present predominantly in mature pollen and growing pollen tubes.
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    Genomic context

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    See PRF5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (8519485..8521275, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene profilin 1 Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene SNARE-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Profilin promotes formin-mediated actin filament assembly and vesicle transport during polarity formation in pollen. Liu C, et al. Plant Cell, 2021 May 31. PMID 33638636
    2. Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth. Liu X, et al. Mol Plant, 2015 Dec 7. PMID 26433093
    3. Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. Kandasamy MK, et al. Cell Motil Cytoskeleton, 2002 May. PMID 11977080
    4. Molecular dissection of plant cytokinesis and phragmoplast structure: a survey of GFP-tagged proteins. Van Damme D, et al. Plant J, 2004 Nov. PMID 15469496
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Profilin promotes formin-mediated actin filament assembly and vesicle transport during polarity formation in pollen.
      Title: Profilin promotes formin-mediated actin filament assembly and vesicle transport during polarity formation in pollen.
    2. PRF4 and PRF5 regulate actin polymerization in pollen grains and tubes.
      Title: Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_127535.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin monomer binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in phragmoplast HDA PubMed 

    General protein information

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    Preferred Names
    profilin 5
    NP_179567.1
    • profilin 5 (PRF5); CONTAINS InterPro DOMAIN/s: Profilin/allergen (InterPro:IPR002097), Profilin, plant (InterPro:IPR005455); BEST Arabidopsis thaliana protein match is: profilin 4 (TAIR:AT4G29340.1); Has 915 Blast hits to 914 proteins in 244 species: Archae - 0; Bacteria - 2; Metazoa - 138; Fungi - 121; Plants - 583; Viruses - 0; Other Eukaryotes - 71 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8519485..8521275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127535.3 → NP_179567.1  profilin 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179567.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEN1, Q1PF40, Q38905
      UniProtKB/TrEMBL
      A0A178W088, A0A5S9WZE7, A0A654EUD1
      Conserved Domains (1) summary
      pfam00235
      Location:1 → 131
      Profilin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38905.1

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