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    Fam110d family with sequence similarity 110, member D [ Mus musculus (house mouse) ]

    Gene ID: 72690, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fam110dprovided by MGI
    Official Full Name
    family with sequence similarity 110, member Dprovided by MGI
    Primary source
    MGI:MGI:1919940
    See related
    Ensembl:ENSMUSG00000050105 AllianceGenome:MGI:1919940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Grrp1; 2810043G13Rik
    Summary
    Is expressed in several structures, including alimentary system; brain ventricular layer; cranium; limb; and sensory organ epithelium. Orthologous to human FAM110D (family with sequence similarity 110 member D). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in ovary adult (RPKM 9.1), lung adult (RPKM 8.2) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam110d in Genome Data Viewer
    Location:
    4 D2.3; 4 66.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133978413..133993528, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134251102..134266196, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7997 Neighboring gene Zfp593 opposite strand Neighboring gene zinc finger protein 593 Neighboring gene predicted gene, 30191 Neighboring gene predicted gene, 42325 Neighboring gene STARR-positive B cell enhancer ABC_E4679 Neighboring gene PDLIM1 interacting kinase 1 like Neighboring gene tripartite motif-containing 63 Neighboring gene STARR-seq mESC enhancer starr_11671

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Id genes are essential for early heart formation. Cunningham TJ, et al. Genes Dev, 2017 Jul 1. PMID 28794185, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM110D
    Names
    glycine/arginine rich protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099296.2 → NP_001092766.1  protein FAM110D

      See identical proteins and their annotated locations for NP_001092766.1

      Status: VALIDATED

      Source sequence(s)
      BB578755, BC048704
      Consensus CDS
      CCDS38913.1
      UniProtKB/Swiss-Prot
      Q80X91
      Related
      ENSMUSP00000060143.6, ENSMUST00000060050.6
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133978413..133993528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164465.1 → XP_036020358.1  protein FAM110D isoform X2

      UniProtKB/Swiss-Prot
      Q80X91
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    2. XM_006539198.4 → XP_006539261.1  protein FAM110D isoform X2

      See identical proteins and their annotated locations for XP_006539261.1

      UniProtKB/Swiss-Prot
      Q80X91
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    3. XM_006539199.3 → XP_006539262.1  protein FAM110D isoform X2

      See identical proteins and their annotated locations for XP_006539262.1

      UniProtKB/Swiss-Prot
      Q80X91
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    4. XM_036164464.1 → XP_036020357.1  protein FAM110D isoform X2

      UniProtKB/Swiss-Prot
      Q80X91
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    5. XM_006539200.3 → XP_006539263.1  protein FAM110D isoform X2

      See identical proteins and their annotated locations for XP_006539263.1

      UniProtKB/Swiss-Prot
      Q80X91
      Conserved Domains (2) summary
      pfam14160
      Location:141 → 262
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:13 → 41
      FAM110_N; Centrosome-associated N-terminus

    6. XM_006539197.4 → XP_006539260.1  protein FAM110D isoform X1

      Conserved Domains (2) summary
      pfam14160
      Location:173 → 294
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:45 → 73
      FAM110_N; Centrosome-associated N-terminus
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80X91.2 GenPept UniProtKB/Swiss-Prot:Q80X91

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