Wdr27 WD repeat domain 27 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wdr27provided by MGI
Official Full Name: WD repeat domain 27provided by MGI
Primary source: MGI:MGI:1918932
See related: Ensembl:ENSMUSG00000046991 AllianceGenome:MGI:1918932
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 0610012K18Rik
Summary: Predicted to be located in nucleoplasm. Orthologous to human WDR27 (WD repeat domain 27). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in testis adult (RPKM 4.5), ovary adult (RPKM 0.4) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 17 A2; 17 8.95 cM

Exon count:: 33

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (15005092..15163540, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (14784829..14943259, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: WD repeat-containing protein 27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175173.3 → NP_780382.2 WD repeat-containing protein 27

See identical proteins and their annotated locations for NP_780382.2

Status: VALIDATED

Source sequence(s)

AK077050, AV277048

Consensus CDS

CCDS37443.1

UniProtKB/Swiss-Prot

Q8C5V5, Q8CA00

Related

ENSMUSP00000153717.2, ENSMUST00000228330.2

Conserved Domains (3) summary

COG2319
Location:53 → 236

WD40; WD40 repeat [General function prediction only]

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl02567
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000083.7 Reference GRCm39 C57BL/6J

Range

15005092..15163540 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006524929.5 → XP_006524992.1 WD repeat-containing protein 27 isoform X4

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 811

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011246612.4 → XP_011244914.1 WD repeat-containing protein 27 isoform X3

See identical proteins and their annotated locations for XP_011244914.1

UniProtKB/TrEMBL

A0A338P6H6

Related

ENSMUSP00000155992.2, ENSMUST00000232147.2

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 822

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524928.3 → XP_006524991.1 WD repeat-containing protein 27 isoform X3

See identical proteins and their annotated locations for XP_006524991.1

UniProtKB/TrEMBL

A0A338P6H6

Related

ENSMUSP00000158649.2, ENSMUST00000238668.2

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 822

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017317639.1 → XP_017173128.1 WD repeat-containing protein 27 isoform X1

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 813

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017317640.3 → XP_017173129.1 WD repeat-containing protein 27 isoform X5

Conserved Domains (2) summary

sd00039
Location:450 → 487

7WD40; WD40 repeat [structural motif]

cl29593
Location:450 → 749

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524925.5 → XP_006524988.1 WD repeat-containing protein 27 isoform X1

See identical proteins and their annotated locations for XP_006524988.1

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 813

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524926.5 → XP_006524989.1 WD repeat-containing protein 27 isoform X1

See identical proteins and their annotated locations for XP_006524989.1

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 813

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524934.4 → XP_006524997.1 WD repeat-containing protein 27 isoform X8

Conserved Domains (2) summary

sd00039
Location:278 → 315

7WD40; WD40 repeat [structural motif]

cl29593
Location:278 → 577

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011246611.3 → XP_011244913.1 WD repeat-containing protein 27 isoform X2

Conserved Domains (2) summary

sd00039
Location:514 → 551

7WD40; WD40 repeat [structural motif]

cl29593
Location:514 → 811

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011246616.3 → XP_011244918.1 WD repeat-containing protein 27 isoform X7

See identical proteins and their annotated locations for XP_011244918.1

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524931.4 → XP_006524994.1 WD repeat-containing protein 27 isoform X6

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011246617.4 → XP_011244919.1 WD repeat-containing protein 27 isoform X7

See identical proteins and their annotated locations for XP_011244919.1

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017317641.3 → XP_017173130.1 WD repeat-containing protein 27 isoform X9

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017317642.3 → XP_017173131.1 WD repeat-containing protein 27 isoform X10

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006524936.3 → XP_006524999.1 WD repeat-containing protein 27 isoform X11

Conserved Domains (2) summary

sd00039
Location:73 → 118

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 235

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...