naa60 N-alpha-acetyltransferase 60, NatF catalytic subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: naa60provided by ZNC
Official Full Name: N-alpha-acetyltransferase 60, NatF catalytic subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041111-143
See related: Ensembl:ENSDARG00000061185 AllianceGenome:ZFIN:ZDB-GENE-041111-143
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: HAT4; NatF; nat15; im:7141641; zgc:163109
Summary: Predicted to enable histone H4 acetyltransferase activity; peptide alpha-N-acetyltransferase activity; and protein homodimerization activity. Predicted to be involved in several processes, including N-terminal peptidyl-methionine acetylation; chromosome segregation; and nucleosome assembly. Predicted to act upstream of or within chromatin organization. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Orthologous to human NAA60 (N-alpha-acetyltransferase 60, NatF catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (27786687..27796349)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (27655845..27665507)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables histone H4 acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables histone acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables peptide alpha-N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptide alpha-N-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables peptide alpha-N-acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-terminal peptidyl-methionine acetylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in N-terminal protein amino acid acetylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in cell population proliferation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within chromatin organization	IEA Inferred from Electronic Annotation more info
involved_in chromosome segregation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chromosome segregation	IEA Inferred from Electronic Annotation more info
involved_in chromosome segregation	ISS Inferred from Sequence or Structural Similarity more info
involved_in nucleosome assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 60

Names: N-acetyltransferase 15 (GCN5-related, putative); N-alpha-acetyltransferase F; histone acetyltransferase type B protein 4; natF catalytic subunit

NP_001076341.1

EC 2.3.1.259

EC 2.3.1.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082872.1 → NP_001076341.1 N-alpha-acetyltransferase 60

See identical proteins and their annotated locations for NP_001076341.1

Status: PROVISIONAL

Source sequence(s)

BC134236

UniProtKB/Swiss-Prot

A3KPA3

Related

ENSDARP00000081428.4, ENSDART00000086994.5

Conserved Domains (2) summary

COG0456
Location:20 → 166

RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

pfam00583
Location:79 → 156

Acetyltransf_1; Acetyltransferase (GNAT) family