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    QSOX2 quiescin-sulfhydryl oxidase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814654, updated on 18-Sep-2024

    Summary

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    Official Symbol
    QSOX2
    Official Full Name
    quiescin-sulfhydryl oxidase 2
    Primary source
    TAIR:AT2G01270
    Locus tag
    AT2G01270
    See related
    Araport:AT2G01270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtQSOX2; F10A8.15; F10A8_15; quiescin-sulfhydryl oxidase 2
    Summary
    Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. This protein also belongs to the quiescin-sulfhydryl oxidase (QSOX) family, which possess an Erv1-like domain at the COOH terminus in addition to a TRX domain.
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    Genomic context

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    See QSOX2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (139309..142560)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L30/L7 family protein Neighboring gene hypothetical protein (DUF789) Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene miscRNA Neighboring gene Cyclin/Brf1-like TBP-binding protein Neighboring gene ncRNA Neighboring gene ribose-5-phosphate isomerase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis quiescin-sulfhydryl oxidase regulates cation homeostasis at the root symplast-xylem interface. Alejandro S, et al. EMBO J, 2007 Jul 11. PMID 17568770, Free PMC Article
    2. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article
    3. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    4. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    NM_001335047.1
    NM_001335048.1
    NM_126188.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables flavin-dependent sulfhydryl oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi trans cisterna HDA PubMed 
    located_in endosome HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    quiescin-sulfhydryl oxidase 2
    NP_565258.1
    • quiescin-sulfhydryl oxidase 2 (QSOX2); FUNCTIONS IN: thiol oxidase activity; INVOLVED IN: oxidation reduction, cell redox homeostasis; LOCATED IN: Golgi apparatus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Erv1/Alr (InterPro:IPR006863), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), ERV/ALR sulphydryl oxidase (InterPro:IPR017905), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: quiescin-sulfhydryl oxidase 1 (TAIR:AT1G15020.1); Has 2833 Blast hits to 2194 proteins in 312 species: Archae - 22; Bacteria - 32; Metazoa - 1533; Fungi - 396; Plants - 476; Viruses - 0; Other Eukaryotes - 374 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      139309..142560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126188.4 → NP_565258.1  quiescin-sulfhydryl oxidase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565258.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94C52, Q9ZU40
      UniProtKB/TrEMBL
      A0A5S9WW95, A0A654ER14
      Conserved Domains (2) summary
      pfam04777
      Location:300 → 390
      Evr1_Alr; Erv1 / Alr family
      cl00388
      Location:35 → 155
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    2. NM_001335047.1 → NP_001324094.1  quiescin-sulfhydryl oxidase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VNT1, A0A1P8AZ38

    3. NM_001335048.1 → NP_001324093.1  quiescin-sulfhydryl oxidase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VNT1, A0A1P8AZ38
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZU40.2

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