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    ATH13 ABC2 homolog 13 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836618, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATH13
    Official Full Name
    ABC2 homolog 13
    Primary source
    TAIR:AT5G64940
    Locus tag
    AT5G64940
    See related
    Araport:AT5G64940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    A. THALIANA OXIDATIVE STRESS-RELATED ABC1-LIKE PROTEIN 1; ABC2 homolog 13; ARABIDOPSIS THALIANA ABC2 HOMOLOG 13; ATATH13; ATOSA1; MXK3.17; MXK3_17; OSA1; OXIDATIVE STRESS-RELATED ABC1-LIKE PROTEIN 1
    Summary
    Encodes a member of ATH subfamily of ATP-binding cassette (ABC) proteins.
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    Genomic context

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    See ATH13 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    20
    Sequence:
    Chromosome: 5; NC_003076.8 (25948954..25953823)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene COP1-interacting protein 8 Neighboring gene CPR5 protein Neighboring gene Mitochondrial transcription termination factor family protein Neighboring gene cyclin dependent kinase group C2 Neighboring gene Mitochondrial substrate carrier family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of the Atypical Kinases ABC1K7 and ABC1K8 Changes the Lipid Composition of the Chloroplast Membrane. Manara A, et al. Plant Cell Physiol, 2015 Jun. PMID 25809944
    2. AtSIA1 AND AtOSA1: two Abc1 proteins involved in oxidative stress responses and iron distribution within chloroplasts. Manara A, et al. New Phytol, 2014 Jan. PMID 24117441
    3. AtOSA1, a member of the Abc1-like family, as a new factor in cadmium and oxidative stress response. Jasinski M, et al. Plant Physiol, 2008 Jun. PMID 18390807, Free PMC Article
    4. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
    5. The Arabidopsis Proteins AtNHR2A and AtNHR2B Are Multi-Functional Proteins Integrating Plant Immunity With Other Biological Processes. Singh R, et al. Front Plant Sci, 2020. PMID 32194606, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ABC1K7 and ABC1K8 influence chloroplast lipid synthesis or accumulation and modulate chloroplast membrane composition in response to stress.[ABC1k8]
      Title: Loss of the Atypical Kinases ABC1K7 and ABC1K8 Changes the Lipid Composition of the Chloroplast Membrane.
    2. AtSIA1 and AtOSA1 are associated with iron distribution within chloroplasts.
      Title: AtSIA1 AND AtOSA1: two Abc1 proteins involved in oxidative stress responses and iron distribution within chloroplasts.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125893.5
    NM_180940.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to oxidative stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in leaf senescence IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within membrane lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of response to reactive oxygen species IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cadmium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to high light intensity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to hydrogen peroxide IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to iron ion starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    ABC2 homolog 13
    NP_201299.2
    • ABC2 homolog 13 (ATH13); FUNCTIONS IN: transporter activity; INVOLVED IN: transport; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ABC-1 (InterPro:IPR004147), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G07700.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_851271.1
    • ABC2 homolog 13 (ATH13); FUNCTIONS IN: transporter activity; INVOLVED IN: transport; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ABC-1 (InterPro:IPR004147), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G07700.2); Has 10051 Blast hits to 9997 proteins in 1795 species: Archae - 126; Bacteria - 4380; Metazoa - 442; Fungi - 487; Plants - 725; Viruses - 14; Other Eukaryotes - 3877 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25948954..25953823
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125893.5 → NP_201299.2  ABC2 homolog 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201299.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLU3, Q93Y08, Q9ASU3, Q9LV84
      UniProtKB/TrEMBL
      A0A178UDV1, A0A5S9YH98, A0A7G2FJW0
      Conserved Domains (1) summary
      COG0661
      Location:178 → 719
      AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]

    2. NM_180940.2 → NP_851271.1  ABC2 homolog 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851271.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLU3, Q93Y08, Q9ASU3, Q9LV84
      UniProtKB/TrEMBL
      A0A178UDV1, A0A5S9YH98, A0A7G2FJW0
      Conserved Domains (1) summary
      COG0661
      Location:178 → 719
      AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93Y08.1

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