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    BAG2 BCL-2-associated athanogene 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836330, updated on 18-Sep-2024

    Summary

    Official Symbol
    BAG2
    Official Full Name
    BCL-2-associated athanogene 2
    Primary source
    TAIR:AT5G62100
    Locus tag
    AT5G62100
    See related
    Araport:AT5G62100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATBAG2; BCL-2-associated athanogene 2; MTG10.13; MTG10_13
    Summary
    A member of Arabidopsis BAG (Bcl-2-associated athanogene) proteins, plant homologs of mammalian regulators of apoptosis. Plant BAG proteins are multi-functional and remarkably similar to their animal counterparts, as they regulate apoptotic-like processes ranging from pathogen attack, to abiotic stress, to plant development.
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    Genomic context

    See BAG2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (24940203..24942003)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene SEUSS-like 2 Neighboring gene Homeodomain-like superfamily protein Neighboring gene response regulator 23

    General gene information

    NM_001345521.1
    NM_001345523.1
    NM_001345524.1
    NM_125603.3
    NM_180915.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
     
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    BCL-2-associated athanogene 2
    NP_001318862.1
    • BCL-2-associated athanogene 2 (BAG2); INVOLVED IN: apoptosis; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, male gametophyte, carpel; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Apoptosis regulator, Bcl-2 protein, BAG (InterPro:IPR003103), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: BCL-2-associated athanogene 3 (TAIR:AT5G07220.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_568950.2
    • BCL-2-associated athanogene 2 (BAG2); INVOLVED IN: apoptosis; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, male gametophyte, carpel; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Apoptosis regulator, Bcl-2 protein, BAG (InterPro:IPR003103), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: BCL-2-associated athanogene 3 (TAIR:AT5G07220.1); Has 234 Blast hits to 234 proteins in 26 species: Archae - 0; Bacteria - 2; Metazoa - 12; Fungi - 4; Plants - 214; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).
    NP_851246.1
    • BCL-2-associated athanogene 2 (BAG2); INVOLVED IN: apoptosis; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, male gametophyte, carpel; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Apoptosis regulator, Bcl-2 protein, BAG (InterPro:IPR003103), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: BCL-2-associated athanogene 3 (TAIR:AT5G07220.1); Has 228 Blast hits to 228 proteins in 24 species: Archae - 0; Bacteria - 0; Metazoa - 9; Fungi - 4; Plants - 213; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24940203..24942003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345522.1NP_001332748.1  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3J8
      Conserved Domains (2) summary
      pfam02179
      Location:133195
      BAG; BAG domain
      cl28922
      Location:39107
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    2. NM_125603.3NP_568950.2  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568950.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K550, Q0WPX7, Q8LEP8, Q9FIS8
      UniProtKB/TrEMBL
      A0A178UE91, A0A5S9YGF9
      Conserved Domains (2) summary
      pfam02179
      Location:133209
      BAG; BAG domain
      cl28922
      Location:39107
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    3. NM_001345521.1NP_001318862.1  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H4L7
    4. NM_001345523.1NP_001332747.1  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UCR2, A0A1R7T3J7, A0A384KUN5
      Conserved Domains (2) summary
      pfam02179
      Location:133196
      BAG; BAG domain
      cl28922
      Location:39107
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    5. NM_001345524.1NP_001332749.1  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H4L7
    6. NM_180915.1NP_851246.1  BCL-2-associated athanogene 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851246.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WPX7
      Conserved Domains (2) summary
      cd01812
      Location:39109
      BAG1_N; Ubiquitin-like domain of BAG1
      pfam02179
      Location:133219
      BAG; BAG domain