PrfB3 peptide chain release factor [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PrfB3
Official Full Name: peptide chain release factor
Primary source: TAIR:AT3G57190
Locus tag: AT3G57190
See related: Araport:AT3G57190
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: peptide chain release factor 3
Summary: Encodes a chloroplast stroma-localized ribosomal peptide chain release factor that is involved in the light- and stress-dependent regulation of stability of 3' processed petB transcripts to adjust cytochrome b(6) levels. It appears to bind to the 3'-UTR of petB RNA, protecting it from 3'-5' exonucleolytic attack. At-prfB3 arose from a gene duplication of At-prfB1.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Data show that PrfB3 is localized to the chloroplast stroma in a petB RNA-containing complex and found only in vascular plants. [PRFB3]
Title: Recruitment of a ribosomal release factor for light- and stress-dependent regulation of petB transcript stability in Arabidopsis chloroplasts.

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NM_115579.3

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables translation release factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloroplast organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of mRNA stability	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in translational termination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed

NP_191278.2

peptide chain release factor, putative; FUNCTIONS IN: translation release factor activity, codon specific, translation release factor activity; INVOLVED IN: translational termination; LOCATED IN: cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Class I peptide chain release factor (InterPro:IPR000352), Peptide chain release factor (InterPro:IPR005139); BEST Arabidopsis thaliana protein match is: high chlorophyll fluorescent 109 (TAIR:AT5G36170.2); Has 13500 Blast hits to 13496 proteins in 2706 species: Archae - 0; Bacteria - 9313; Metazoa - 113; Fungi - 108; Plants - 181; Viruses - 0; Other Eukaryotes - 3785 (source: NCBI BLink).