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    PHATRDRAFT_52412 channel voltage activated chloride channel [ Phaeodactylum tricornutum CCAP 1055/1 ]

    Gene ID: 7203690, updated on 21-Dec-2023

    Summary

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    Gene symbol
    PHATRDRAFT_52412
    Gene description
    channel voltage activated chloride channel
    Locus tag
    PHATRDRAFT_52412
    Gene type
    protein coding
    RNA name
    channel voltage activated chloride channel
    RefSeq status
    PROVISIONAL
    Organism
    Phaeodactylum tricornutum CCAP 1055/1 (strain: CCAP 1055/1)
    Lineage
    Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum
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    Genomic context

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    See PHATRDRAFT_52412 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    2
    Sequence:
    Chromosome: 17; NC_011685.1 (552281..554474, complement)

    Chromosome 17 - NC_011685.1Genomic Context describing neighboring genes Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene delta 5 fatty acid desaturase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_011685.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Bowler C, et al. Nature, 2008 Nov 13. PMID 18923393
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Names
    channel voltage activated chloride channel
    XP_002182982.1
    • Has conserved features of animal voltage activated ion channel CLC7 group. 10-12 TM domains and C terminus also has 2 CBS binding domains typical of these channels. Phylogenetic analysis of putative AA clusters along with T. pseudonana CLC7 ortholog in animal CLC7 group.

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_011685.1 Reference assembly

      Range
      552281..554474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002182946.2 → XP_002182982.1  channel voltage activated chloride channel [Phaeodactylum tricornutum CCAP 1055/1]

      See identical proteins and their annotated locations for XP_002182982.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      B7G775
      Conserved Domains (4) summary
      COG0517
      Location:617 → 667
      CBS; CBS domain [Signal transduction mechanisms]
      cd04591
      Location:614 → 667
      CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
      pfam00654
      Location:40 → 465
      Voltage_CLC; Voltage gated chloride channel
      cl02915
      Location:30 → 484
      Voltage_gated_ClC; CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This ...
    Nucleotide Protein
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