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    Rnf34 ring finger protein 34 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101725498, updated on 3-Dec-2024

    Summary

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    Gene symbol
    Rnf34
    Gene description
    ring finger protein 34
    See related
    Ensembl:ENSHGLG00000013371
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf34 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624747.1 (21904652..21920579)

    NW_004624747.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110348917 Neighboring gene calcium/calmodulin dependent protein kinase kinase 2 Neighboring gene anaphase promoting complex subunit 5 Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene lysine demethylase 2B Neighboring gene uncharacterized LOC106009288

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624747 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624747.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      21904652..21920579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004843844.2 → XP_004843901.2  E3 ubiquitin-protein ligase RNF34 isoform X1

      UniProtKB/TrEMBL
      A0AAX6P4W7
      Conserved Domains (1) summary
      cd15769
      Location:172 → 218
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins

    2. XM_013071790.2 → XP_012927244.2  E3 ubiquitin-protein ligase RNF34 isoform X2

      UniProtKB/TrEMBL
      A0AAX6QW81
      Conserved Domains (2) summary
      cd15769
      Location:172 → 218
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins
      cd16706
      Location:443 → 481
      RING-HC_CARP1; RING finger, HC subclass, found in caspases-8 and -10-associated RING finger protein 1 (CARP1) and similar proteins

    3. XM_021257513.1 → XP_021113172.1  E3 ubiquitin-protein ligase RNF34 isoform X3

      UniProtKB/TrEMBL
      A0AAX6STV6
      Related
      ENSHGLP00000018672.1, ENSHGLT00000018858.1
      Conserved Domains (1) summary
      cd15769
      Location:82 → 128
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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