ZBTB7B zinc finger and BTB domain containing 7B [Homo sapiens (human)] - Gene

Summary

Official Symbol: ZBTB7Bprovided by HGNC
Official Full Name: zinc finger and BTB domain containing 7Bprovided by HGNC
Primary source: HGNC:HGNC:18668
See related: Ensembl:ENSG00000160685 MIM:607646; AllianceGenome:HGNC:18668
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: vGAF; CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
Summary: This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Expression: Broad expression in skin (RPKM 39.5), duodenum (RPKM 31.2) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 1q21.3

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (155001750..155018523)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (154140715..154157896)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (154975125..154990999)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ALDH1A1 promotes immune escape of tumor cells through ZBTB7B-glycolysis pathway.
Title: ALDH1A1 promotes immune escape of tumor cells through ZBTB7B-glycolysis pathway.
A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.
Title: A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.
Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4(+)CD8(+) T cells in ulcerative colitis.
Title: Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4(+)CD8(+) T cells in ulcerative colitis.
ThPOK transcriptionally inactivates TNFRSF12A to increase the proliferation of T cells with the involvement of the NF-kB pathway.
Title: ThPOK transcriptionally inactivates TNFRSF12A to increase the proliferation of T cells with the involvement of the NF-kB pathway.
Zbtb7a and Zbtb7b: Opening naive loci to reprogram ESCs.
Title: Zbtb7a and Zbtb7b: Opening naïve loci to reprogram ESCs.
Zbtb7b suppresses aseptic inflammation by regulating m(6)A modification of IL6 mRNA.
Title: Zbtb7b suppresses aseptic inflammation by regulating m(6)A modification of IL6 mRNA.
Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
Title: Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
In vitro, prolonged activation of naive CD4 T cells in presence of Th1 polarizing cytokines led to the acquisition of perforin-dependent cytotoxic activity. This process was dependent on the Th1 transcription factor Runx3 and was limited by the sustained expression of ThPOK.
Title: The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes.
Authors show that the transcription factor ThPOK binds cooperatively with NF-kappaB to NRCs and mediates their physical proximity with the IFNB1 gene via its ability to oligomerize when bound to DNA.
Title: The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.
a novel pathway by which TIP60 and ThPOK synergistically suppresses Eomes function and IFNgamma production, which could contribute to the regulation of inflammation.
Title: 60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells.

Submit: New GeneRIF Correction See all GeneRIFs (21)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A novel common variant in DCST2 is associated with length in early life and height in adulthood. EBI GWAS Catalog EBI GWAS CatalogPubMed
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZFP67__4945 (e-PCR)
- UniSTS:468805

L17988 (e-PCR)
- UniSTS:80500

SHGC-84651 (e-PCR)
- UniSTS:103138

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription repressor activity	ISS Inferred from Sequence or Structural Similarity more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone deacetylase binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables sequence-specific double-stranded DNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in NK T cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in adaptive thermogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in ectoderm development	TAS Traceable Author Statement more info	PubMed
involved_in lactation	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of CD8-positive, alpha-beta T cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of NK T cell proliferation	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of T-helper 17 cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of gene expression	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of CD4-positive, alpha-beta T cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of SREBP signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of brown fat cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of cold-induced thermogenesis	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of gene expression	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of gene expression	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of insulin receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of interleukin-17 production	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to insulin	ISS Inferred from Sequence or Structural Similarity more info
involved_in transcription by RNA polymerase II	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in nucleoplasm	IDA Inferred from Direct Assay more info

General protein information

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Preferred Names: zinc finger and BTB domain-containing protein 7B

Names: T-helper-inducing POZ/Krueppel-like factor; krueppel-related zinc finger protein cKrox; zinc finger and BTB domain containing 15; zinc finger protein 67 homolog; zinc finger protein 857B; zinc finger protein Th-POK

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001252406.3 → NP_001239335.1 zinc finger and BTB domain-containing protein 7B isoform 2

See identical proteins and their annotated locations for NP_001239335.1

Status: REVIEWED

Description

Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (2).

Source sequence(s)

AI270090, AK304762, AL451085, BC012070, CV572166, DB241444

Consensus CDS

CCDS58030.1

UniProtKB/TrEMBL

A8K6F4

Related

ENSP00000406286.2, ENST00000417934.6

Conserved Domains (3) summary

sd00017
Location:410 → 430

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:43 → 176

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:397 → 419

zf-H2C2_2; Zinc-finger double domain
NM_001256455.2 → NP_001243384.1 zinc finger and BTB domain-containing protein 7B isoform 1

See identical proteins and their annotated locations for NP_001243384.1

Status: REVIEWED

Description

Transcript Variant: This variant (5) lacks two alternate exons in the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, comapred to variant 3. The encoded isoform (1) is shorter at the N-terminus, compared to isoform 2.

Source sequence(s)

AI270090, AL451085, BC012070, CV572166

Consensus CDS

CCDS1081.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Related

ENSP00000438647.1, ENST00000535420.6

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
NM_001377451.1 → NP_001364380.1 zinc finger and BTB domain-containing protein 7B isoform 2

Status: REVIEWED

Source sequence(s)

AL451085

Consensus CDS

CCDS58030.1

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (3) summary

sd00017
Location:410 → 430

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:43 → 176

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:397 → 419

zf-H2C2_2; Zinc-finger double domain
NM_001377452.1 → NP_001364381.1 zinc finger and BTB domain-containing protein 7B isoform 1

Status: REVIEWED

Source sequence(s)

AL451085

Consensus CDS

CCDS1081.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
NM_001377453.1 → NP_001364382.1 zinc finger and BTB domain-containing protein 7B isoform 1

Status: REVIEWED

Source sequence(s)

AL451085

Consensus CDS

CCDS1081.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Related

ENSP00000357411.3, ENST00000368426.3

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
NM_001377454.1 → NP_001364383.1 zinc finger and BTB domain-containing protein 7B isoform 1

Status: REVIEWED

Source sequence(s)

AL451085

Consensus CDS

CCDS1081.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
NM_001377455.1 → NP_001364384.1 zinc finger and BTB domain-containing protein 7B isoform 1

Status: REVIEWED

Source sequence(s)

AL451085

Consensus CDS

CCDS1081.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000001.11 Reference GRCh38.p14 Primary Assembly

Range

155001750..155018523

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047421851.1 → XP_047277807.1 zinc finger and BTB domain-containing protein 7B isoform X2
XM_006711359.3 → XP_006711422.1 zinc finger and BTB domain-containing protein 7B isoform X5

See identical proteins and their annotated locations for XP_006711422.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
XM_047421865.1 → XP_047277821.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_047421871.1 → XP_047277827.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

Related

ENSP00000292176.2, ENST00000292176.2
XM_047421852.1 → XP_047277808.1 zinc finger and BTB domain-containing protein 7B isoform X3
XM_047421858.1 → XP_047277814.1 zinc finger and BTB domain-containing protein 7B isoform X4
XM_047421894.1 → XP_047277850.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_011509599.3 → XP_011507901.1 zinc finger and BTB domain-containing protein 7B isoform X5

See identical proteins and their annotated locations for XP_011507901.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
XM_047421853.1 → XP_047277809.1 zinc finger and BTB domain-containing protein 7B isoform X4
XM_047421876.1 → XP_047277832.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_047421868.1 → XP_047277824.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_047421854.1 → XP_047277810.1 zinc finger and BTB domain-containing protein 7B isoform X4
XM_047421883.1 → XP_047277839.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_017001399.2 → XP_016856888.1 zinc finger and BTB domain-containing protein 7B isoform X1

UniProtKB/TrEMBL

A8K6F4
XM_006711356.4 → XP_006711419.1 zinc finger and BTB domain-containing protein 7B isoform X5

See identical proteins and their annotated locations for XP_006711419.1

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

UniProtKB/TrEMBL

A8K6F4

Conserved Domains (4) summary

COG5048
Location:345 → 424

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:376 → 396

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18327
Location:9 → 142

BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)

pfam13465
Location:363 → 385

zf-H2C2_2; Zinc-finger double domain
XM_047421863.1 → XP_047277819.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

Alternate T2T-CHM13v2.0

Genomic

NC_060925.1 Alternate T2T-CHM13v2.0

Range

154140715..154157896

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054336854.1 → XP_054192829.1 zinc finger and BTB domain-containing protein 7B isoform X2
XM_054336857.1 → XP_054192832.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336860.1 → XP_054192835.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336862.1 → XP_054192837.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336856.1 → XP_054192831.1 zinc finger and BTB domain-containing protein 7B isoform X4
XM_054336859.1 → XP_054192834.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336855.1 → XP_054192830.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336863.1 → XP_054192838.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336853.1 → XP_054192828.1 zinc finger and BTB domain-containing protein 7B isoform X1
XM_054336861.1 → XP_054192836.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
XM_054336858.1 → XP_054192833.1 zinc finger and BTB domain-containing protein 7B isoform X5

UniProtKB/Swiss-Prot

B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2