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    Protein with RING/U-box and TRAF-like domain [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833768, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein with RING/U-box and TRAF-like domain
    Primary source
    TAIR:AT5G37890
    Locus tag
    AT5G37890
    See related
    Araport:AT5G37890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSINAL7; K18L3.9; K18L3_9; SINA like 7; SINAL7
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (15089678..15091955, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene TRAF-like superfamily protein Neighboring gene Protein with RING/U-box and TRAF-like domain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Over-expression of SINAL7 increases biomass and drought tolerance, and also delays senescence in Arabidopsis. Peralta DA, et al. J Biotechnol, 2018 Oct 10. PMID 30003973
    2. Characterization of the Arabidopsis thaliana E3 ubiquitin-ligase AtSINAL7 and identification of the ubiquitination sites. Peralta DA, et al. PLoS One, 2013. PMID 24015288, Free PMC Article
    3. The E3 ubiquitin-ligase SEVEN IN ABSENTIA like 7 mono-ubiquitinates glyceraldehyde-3-phosphate dehydrogenase 1 isoform in vitro and is required for its nuclear localization in Arabidopsis thaliana. Peralta DA, et al. Int J Biochem Cell Biol, 2016 Jan. PMID 26582368
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study showed that SINAL7 over-expression had a positive effect on vegetative growth in Arabidopsis, resulting in sucrose and hexose levels increase and leading to a higher biomass content associated with stomatal closure and drought tolerance. The SINAL7-over-expressing plants showed a delay in senescence, with no signs of aging at the transcriptional level and in terms of chlorophyll content or leaf yellowing.
      Title: Over-expression of SINAL7 increases biomass and drought tolerance, and also delays senescence in Arabidopsis.
    2. Data suggests a role for SINAL7 in the regulation of both, the activity and the localization of GAPC1 that could be relevant to the physiology of plant cells. [SINAl7]
      Title: The E3 ubiquitin-ligase SEVEN IN ABSENTIA like 7 mono-ubiquitinates glyceraldehyde-3-phosphate dehydrogenase 1 isoform in vitro and is required for its nuclear localization in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123148.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein with RING/U-box and TRAF-like domain
    NP_198605.2
    • Protein with RING/U-box and TRAF-like domains; FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: multicellular organismal development, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus, intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, SIAH-type (InterPro:IPR013010), Zinc finger, RING-type (InterPro:IPR001841), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT5G37910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15089678..15091955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123148.4 → NP_198605.2  Protein with RING/U-box and TRAF-like domain [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198605.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FKD7
      UniProtKB/TrEMBL
      A0A178UNQ6, A0A654G6T5
      Conserved Domains (2) summary
      cd16571
      Location:49 → 86
      RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
      cl19105
      Location:94 → 164
      Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FKD7.1

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