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    RECQSIM RECQ helicase SIM [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832830, updated on 18-Sep-2024

    Summary

    Official Symbol
    RECQSIM
    Official Full Name
    RECQ helicase SIM
    Primary source
    TAIR:AT5G27680
    Locus tag
    AT5G27680
    See related
    Araport:AT5G27680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RECQ helicase SIM; T1G16.10; T1G16_10
    Summary
    DNA helicase
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    Genomic context

    See RECQSIM in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (9793745..9799149, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Trypsin family protein with PDZ domain-containing protein Neighboring gene histone H2A 7 Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene Ribosomal protein S21e

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001344027.1
    NM_001344029.1
    NM_001344030.1
    NM_001344031.1
    NM_122650.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA duplex unwinding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA repair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    RECQ helicase SIM
    NP_568499.1
    • RECQ helicase SIM (RECQSIM); FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: RECQ helicase L2 (TAIR:AT1G31360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9793745..9799149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344028.1NP_001330796.1  RECQ helicase SIM [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FT69
      UniProtKB/TrEMBL
      A0A5S9Y833
      Conserved Domains (5) summary
      smart00487
      Location:162355
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:486600
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:170341
      DEAD; DEAD/DEAH box helicase
      pfam16124
      Location:612663
      RecQ_Zn_bind; RecQ zinc-binding
      cl21463
      Location:842
      UBA_like_SF; UBA domain-like superfamily
    2. NM_122650.5NP_568499.1  RECQ helicase SIM [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568499.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FT69
      UniProtKB/TrEMBL
      A0A5S9Y833
      Conserved Domains (5) summary
      smart00487
      Location:162355
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:486600
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:170341
      DEAD; DEAD/DEAH box helicase
      pfam16124
      Location:612663
      RecQ_Zn_bind; RecQ zinc-binding
      cl21463
      Location:842
      UBA_like_SF; UBA domain-like superfamily
    3. NM_001344027.1NP_001330792.1  RECQ helicase SIM [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FT69
      UniProtKB/TrEMBL
      A0A5S9Y833
      Conserved Domains (5) summary
      smart00487
      Location:162355
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:486600
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:170341
      DEAD; DEAD/DEAH box helicase
      pfam16124
      Location:612663
      RecQ_Zn_bind; RecQ zinc-binding
      cl21463
      Location:842
      UBA_like_SF; UBA domain-like superfamily
    4. NM_001344029.1NP_001330794.1  RECQ helicase SIM [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FT69
      UniProtKB/TrEMBL
      A0A5S9Y833
      Conserved Domains (5) summary
      smart00487
      Location:162355
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:486600
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:170341
      DEAD; DEAD/DEAH box helicase
      pfam16124
      Location:612663
      RecQ_Zn_bind; RecQ zinc-binding
      cl21463
      Location:842
      UBA_like_SF; UBA domain-like superfamily
    5. NM_001344030.1NP_001330793.1  RECQ helicase SIM [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBY3, A0A5S9Y833
    6. NM_001344031.1NP_001330795.1  RECQ helicase SIM [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBY0, A0A5S9Y833