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    DHS deoxyhypusine synthase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830477, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DHS
    Official Full Name
    deoxyhypusine synthase
    Primary source
    TAIR:AT5G05920
    Locus tag
    AT5G05920
    See related
    Araport:AT5G05920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    deoxyhypusine synthase; EDA22; embryo sac development arrest 22; K18J17.7; K18J17_7
    Summary
    Encodes a deoxyhypusine synthase.
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    Genomic context

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    See DHS in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (1777547..1779867, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene RING/U-box superfamily protein Neighboring gene guanylyl cyclase 1 Neighboring gene ROP guanine nucleotide exchange factor 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Repeated evolution of the pyrrolizidine alkaloid-mediated defense system in separate angiosperm lineages. Reimann A, et al. Plant Cell, 2004 Oct. PMID 15466410, Free PMC Article
    2. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001342839.1
    NM_001342840.1
    NM_120674.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables deoxyhypusine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    deoxyhypusine synthase
    NP_001318486.1
    • deoxyhypusine synthase (DHS); INVOLVED IN: embryo sac development, peptidyl-lysine modification to hypusine; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Deoxyhypusine synthase (InterPro:IPR002773); Has 2057 Blast hits to 2052 proteins in 494 species: Archae - 295; Bacteria - 232; Metazoa - 167; Fungi - 158; Plants - 157; Viruses - 0; Other Eukaryotes - 1048 (source: NCBI BLink).
    NP_196211.1
    • deoxyhypusine synthase (DHS); INVOLVED IN: embryo sac development, peptidyl-lysine modification to hypusine; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Deoxyhypusine synthase (InterPro:IPR002773); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1777547..1779867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120674.4 → NP_196211.1  deoxyhypusine synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196211.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ASU5, Q9C5Y5, Q9FI94
      UniProtKB/TrEMBL
      A0A178U8Y5, A0A7G2FB90
      Conserved Domains (1) summary
      pfam01916
      Location:42 → 353
      DS; Deoxyhypusine synthase

    2. NM_001342840.1 → NP_001330195.1  deoxyhypusine synthase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BA27

    3. NM_001342839.1 → NP_001318486.1  deoxyhypusine synthase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K292
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FI94.1

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