ROC5 rotamase cyclophilin 5 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ROC5
Official Full Name: rotamase cyclophilin 5
Primary source: TAIR:AT4G34870
Locus tag: AT4G34870
See related: Araport:AT4G34870
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA CYCLOPHILIN 1; ATCYP1; CYCLOPHILIN; rotamase cyclophilin 5; ROTAMASE CYP
Summary: belongs to cyclophilin family
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Genomic context

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See ROC5 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 1

Sequence:: Chromosome: 4; NC_003075.7 (16614204..16615313)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Ra1F06 (e-PCR), detects polymorphism
- UniSTS:497340

Homology

Orthologs from OrthoDB

NM_119653.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables peptidyl-prolyl cis-trans isomerase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in protein folding	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in apoplast	HDA more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: rotamase cyclophilin 5

NP_195213.1

rotamase cyclophilin 5 (ROC5); FUNCTIONS IN: peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: protein folding, signal transduction; LOCATED IN: cytosol, apoplast, chloroplast, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Cyclophilin-like (InterPro:IPR015891), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type (InterPro:IPR002130), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site (InterPro:IPR020892); BEST Arabidopsis thaliana protein match is: rotamase CYP 3 (TAIR:AT2G16600.1); Has 16787 Blast hits to 16755 proteins in 2701 species: Archae - 108; Bacteria - 6977; Metazoa - 2940; Fungi - 1375; Plants - 1301; Viruses - 4; Other Eukaryotes - 4082 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16614204..16615313

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119653.4 → NP_195213.1 rotamase cyclophilin 5 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195213.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0WRR9, Q42406

UniProtKB/TrEMBL

A0A178UWH6, A0A5S9XZI5

Conserved Domains (1) summary

cd01926
Location:4 → 169

cyclophilin_ABH_like; Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which accelerates protein folding ...