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    TPX2 (targeting protein for Xklp2) protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829367, updated on 18-Sep-2024

    Summary

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    Official Full Name
    TPX2 (targeting protein for Xklp2) protein family
    Primary source
    TAIR:AT4G32330
    Locus tag
    AT4G32330
    See related
    Araport:AT4G32330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F8B4.30
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    9
    Sequence:
    Chromosome: 4; NC_003075.7 (15608905..15612339)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene S-domain-2 5 Neighboring gene ascorbate peroxidase 6 Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene Regulator of Vps4 activity in the MVB pathway protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microtubule bundling plays a role in ethylene-mediated cortical microtubule reorientation in etiolated Arabidopsis hypocotyls. Ma Q, et al. J Cell Sci, 2016 May 15. PMID 27044753
    2. Ethylene Regulates the Arabidopsis Microtubule-Associated Protein WAVE-DAMPENED2-LIKE5 in Etiolated Hypocotyl Elongation. Sun J, et al. Plant Physiol, 2015 Sep. PMID 26134166, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The effects of ethylene on microtubule bundling were partially suppressed in a microtubule-bundling protein WDL5 knockout mutant (wdl5-1). This study suggests that modulation of microtubule bundles that have formed in certain orientations plays a role in reorienting microtubule arrays in response to ethylene-mediated etiolated hypocotyl cell elongation. [WDL5]
      Title: Microtubule bundling plays a role in ethylene-mediated cortical microtubule reorientation in etiolated Arabidopsis hypocotyls.
    2. This study reveals a mechanism involved in the ethylene regulation of microtubules through WDL5 to inhibit etiolated hypocotyl cell elongation.[WDL5]
      Title: Ethylene Regulates the Arabidopsis Microtubule-Associated Protein WAVE-DAMPENED2-LIKE5 in Etiolated Hypocotyl Elongation.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001125622.2
    NM_001342134.1
    NM_119385.3
    NM_202930.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to ethylene stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule bundle formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with cortical microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TPX2 (targeting protein for Xklp2) protein family
    NP_001119094.1
    • TPX2 (targeting protein for Xklp2) protein family; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: TPX2 (targeting protein for Xklp2) protein family (TAIR:AT2G25480.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_567893.1
    • TPX2 (targeting protein for Xklp2) protein family; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: TPX2 (targeting protein for Xklp2) protein family (TAIR:AT2G25480.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974659.1
    • TPX2 (targeting protein for Xklp2) protein family; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: TPX2 (targeting protein for Xklp2) protein family (TAIR:AT2G25480.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15608905..15612339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119385.3 → NP_567893.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567893.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JU98, O49359, Q94C48, Q9SUV5
      UniProtKB/TrEMBL
      A0A178UWB4, A0A7G2F2B9
      Conserved Domains (1) summary
      pfam06886
      Location:207 → 291
      TPX2; Targeting protein for Xklp2 (TPX2)

    2. NM_001125622.2 → NP_001119094.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119094.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JU98, O49359, Q94C48, Q9SUV5
      UniProtKB/TrEMBL
      A0A178UWB4, A0A7G2F2B9
      Conserved Domains (1) summary
      pfam06886
      Location:207 → 291
      TPX2; Targeting protein for Xklp2 (TPX2)

    3. NM_202930.1 → NP_974659.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974659.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2F2N4
      Conserved Domains (1) summary
      pfam06886
      Location:210 → 264
      TPX2; Targeting protein for Xklp2 (TPX2)

    4. NM_001342134.1 → NP_001328200.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JU98, O49359, Q94C48, Q9SUV5
      UniProtKB/TrEMBL
      A0A178UWB4, A0A7G2F2B9
      Conserved Domains (1) summary
      pfam06886
      Location:207 → 291
      TPX2; Targeting protein for Xklp2 (TPX2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94C48.1

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