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    TPX2 (targeting protein for Xklp2) protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821884, updated on 18-Sep-2024

    Summary

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    Official Full Name
    TPX2 (targeting protein for Xklp2) protein family
    Primary source
    TAIR:AT3G23090
    Locus tag
    AT3G23090
    See related
    Araport:AT3G23090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    WDL3
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (8214289..8217206, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene CRM family member 3A Neighboring gene Polyketide cyclase/dehydrase and lipid transport superfamily protein Neighboring gene pseudo Neighboring gene DNA ligase IV-binding protein Neighboring gene receptor like protein 37 Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. COP1 mediates dark-specific degradation of microtubule-associated protein WDL3 in regulating Arabidopsis hypocotyl elongation. Lian N, et al. Proc Natl Acad Sci U S A, 2017 Nov 14. PMID 29087315, Free PMC Article
    2. Light-regulated hypocotyl elongation involves proteasome-dependent degradation of the microtubule regulatory protein WDL3 in Arabidopsis. Liu X, et al. Plant Cell, 2013 May. PMID 23653471, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. COP1 mediates dark-specific degradation of microtubule-associated protein WDL3 in regulating Arabidopsis hypocotyl elongation.
      Title: COP1 mediates dark-specific degradation of microtubule-associated protein WDL3 in regulating Arabidopsis hypocotyl elongation.
    2. Data indicate that overexpression of microtubule regulatory protein WDL3 (At3g23090) inhibited etiolated hypocotyl growth in regulatory particle non-ATPase subunit-1a mutant (rpn1a-4; At2g20580) plants but not in wild-type seedlings.
      Title: Light-regulated hypocotyl elongation involves proteasome-dependent degradation of the microtubule regulatory protein WDL3 in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001338613.1
    NM_001338616.1
    NM_113210.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with cortical microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cortical microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TPX2 (targeting protein for Xklp2) protein family
    NP_001319622.1
    • TPX2 (targeting protein for Xklp2) protein family; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf apex, inflorescence meristem, hypocotyl, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: WVD2-like 1 (TAIR:AT3G04630.3).
    NP_188950.1
    • TPX2 (targeting protein for Xklp2) protein family; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: WVD2-like 1 (TAIR:AT3G04630.3); Has 678 Blast hits to 638 proteins in 104 species: Archae - 2; Bacteria - 22; Metazoa - 209; Fungi - 27; Plants - 299; Viruses - 0; Other Eukaryotes - 119 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8214289..8217206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338615.1 → NP_001326991.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LQY3, A0A5S9XF73
      Conserved Domains (1) summary
      pfam06886
      Location:234 → 288
      TPX2; Targeting protein for Xklp2 (TPX2)

    2. NM_001338614.1 → NP_001326990.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V909, A0A1I9LQY2

    3. NM_001338613.1 → NP_001319622.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V909, F4J2V3
      Conserved Domains (1) summary
      pfam06886
      Location:194 → 282
      TPX2; Targeting protein for Xklp2 (TPX2)

    4. NM_113210.4 → NP_188950.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188950.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84WL6, Q9LS82
      UniProtKB/TrEMBL
      A0A5S9XF73, A0A654FB52
      Conserved Domains (1) summary
      pfam06886
      Location:194 → 278
      TPX2; Targeting protein for Xklp2 (TPX2)

    5. NM_001338616.1 → NP_001326992.1  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V8V6, A0A1I9LQY4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84WL6.1

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