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    PDV2 plastid division2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816104, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PDV2
    Official Full Name
    plastid division2
    Primary source
    TAIR:AT2G16070
    Locus tag
    AT2G16070
    See related
    Araport:AT2G16070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F7H1.9; F7H1_9; PLASTID DIVISION2
    Summary
    An integral outer envelope membrane protein (its homolog in A thaliana PDV1), component of the plastid division machinery. Similar to ARC6, PDV2 localizes to a continuous ring at the division site in wild-type plants. PDV1 and PDV2 are required for localization of ARC5 at the chloroplast division site.
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    Genomic context

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    See PDV2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (6983846..6985620, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene hemoglobin 1 Neighboring gene miscRNA Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PDV2 has a dosage effect on chloroplast division in Arabidopsis. Chang N, et al. Plant Cell Rep, 2017 Mar. PMID 27988788
    2. Structural insights into the coordination of plastid division by the ARC6-PDV2 complex. Wang W, et al. Nat Plants, 2017 Mar 1. PMID 28248291
    3. Phosphatidylinositol 4-phosphate negatively regulates chloroplast division in Arabidopsis. Okazaki K, et al. Plant Cell, 2015 Mar. PMID 25736058, Free PMC Article
    4. PDV1 and PDV2 mediate recruitment of the dynamin-related protein ARC5 to the plastid division site. Miyagishima SY, et al. Plant Cell, 2006 Oct. PMID 16998069, Free PMC Article
    5. PDV1 and PDV2 Differentially Affect Remodeling and Assembly of the Chloroplast DRP5B Ring. Sun B, et al. Plant Physiol, 2020 Apr. PMID 32005784, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PDV1 and PDV2 Differentially Affect Remodeling and Assembly of the Chloroplast DRP5B Ring.
      Title: PDV1 and PDV2 Differentially Affect Remodeling and Assembly of the Chloroplast DRP5B Ring.
    2. PDV2 inserts its carboxy terminus into a pocket formed in ARC6, and this interaction further induces the dimerization of the intermembrane space regions of two ARC6 molecules. A pdv2 mutant attenuating PDV2-induced ARC6 dimerization showed abnormal morphology of ARC6 rings and compromised chloroplast division in plant cells.
      Title: Structural insights into the coordination of plastid division by the ARC6-PDV2 complex.
    3. PDV2 is an important positive factor of chloroplast division with an apparent dosage effect in Arabidopsis.
      Title: PDV2 has a dosage effect on chloroplast division in Arabidopsis.
    4. Data indicate that that PDV1 and PDV2 inhibits DRP5B-mediated GTP hydrolysis in a ratio dependent manner.
      Title: Plastid division control: the PDV proteins regulate DRP5B dynamin activity.
    5. Data show that ARC6 coordinates the division machineries of the inner and outer chloroplast membranes through interaction with PDV2 in the intermembrane space.
      Title: Arabidopsis ARC6 coordinates the division machineries of the inner and outer chloroplast membranes through interaction with PDV2 in the intermembrane space.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001335463.1
    NM_127166.4
    NM_179628.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidylinositol-4-phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloroplast fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plastid fission IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    plastid division2
    NP_028242.1
    • PLASTID DIVISION2 (PDV2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: plastid fission; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: plastid division1 (TAIR:AT5G53280.1); Has 92 Blast hits to 92 proteins in 15 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 2; Plants - 86; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).
    NP_849959.1
    • PLASTID DIVISION2 (PDV2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: plastid fission; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; Has 45 Blast hits to 45 proteins in 11 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 45; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6983846..6985620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127166.4 → NP_028242.1  plastid division2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_028242.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZL0, Q9XII1
      UniProtKB/TrEMBL
      A0A654ET91
      Conserved Domains (1) summary
      TIGR02473
      Location:82 → 135
      flagell_FliJ; flagellar export protein FliJ

    2. NM_001335463.1 → NP_001324370.1  plastid division2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUA9

    3. NM_179628.4 → NP_849959.1  plastid division2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VUA9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XII1.1

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