AIB ABA-inducible BHLH-type transcription factor [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: AIB
Official Full Name: ABA-inducible BHLH-type transcription factor
Primary source: TAIR:AT2G46510
Locus tag: AT2G46510
See related: Araport:AT2G46510
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ABA-inducible BHLH-type transcription factor; ATAIB; F11C10.32; JA-associated MYC2-like 1; JAM1
Summary: Encodes a nuclear localized BLH domain containing transcriptional activator involved in response to ABA. Overexpression confers enhanced ABA responsiveness while loss of function mutants are ABA sensitive.
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Genomic context

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See AIB in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 1

Sequence:: Chromosome: 2; NC_003071.7 (19090953..19093373, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results suggest that JAM1, JAM2, and JAM3 act redundantly as negative regulators of jasmonic acid-mediated male fertility.[JAM1]
Title: Two bHLH-type transcription factors, JA-ASSOCIATED MYC2-LIKE2 and JAM3, are transcriptional repressors and affect male fertility.
JAM1 (At2g46510) negatively regulates the JA response in a manner that is mostly antagonistic to MYC2.
Title: Basic helix-loop-helix transcription factors JASMONATE-ASSOCIATED MYC2-LIKE1 (JAM1), JAM2, and JAM3 are negative regulators of jasmonate responses in Arabidopsis.
Data indicate that JAM1 (AT2G46510) and MYC2 competitively bind to the target sequence of MYC2, which likely provides the mechanism for negative regulation of jasmonates (JAs) signaling and suppression of MYC2 functions by JAM1.
Title: A bHLH-type transcription factor, ABA-INDUCIBLE BHLH-TYPE TRANSCRIPTION FACTOR/JA-ASSOCIATED MYC2-LIKE1, acts as a repressor to negatively regulate jasmonate signaling in arabidopsis.
A few genes having either WRKY or bHLH cis elements in their promoter regions showed higher transcript levels than wild type.
Title: Co-expression of AtbHLH17 and AtWRKY28 confers resistance to abiotic stress in Arabidopsis.
AtAIB functions as a transcription activator involved in the regulation of ABA signaling in Arabidopsis.
Title: The bHLH-type transcription factor AtAIB positively regulates ABA response in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_130216.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of gene expression	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to wounding	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: ABA-inducible BHLH-type transcription factor

NP_566078.1

ABA-inducible BHLH-type transcription factor (AIB); CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G01260.3); Has 3953 Blast hits to 3634 proteins in 219 species: Archae - 0; Bacteria - 0; Metazoa - 70; Fungi - 110; Plants - 3759; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

19090953..19093373 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_130216.3 → NP_566078.1 ABA-inducible BHLH-type transcription factor [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566078.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LPT0, Q9ZPY8

UniProtKB/TrEMBL

A0A178VP13, A0A5S9X7H5, A0A654F2I9

Conserved Domains (2) summary

cd11449
Location:388 → 465

bHLH_AtAIB_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein ABA-INDUCIBLE bHLH-TYPE (AIB) and similar proteins

pfam14215
Location:48 → 239

bHLH-MYC_N; bHLH-MYC and R2R3-MYB transcription factors N-terminal