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    GDI1 guanosine nucleotide diphosphate dissociation inhibitor 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819016, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GDI1
    Official Full Name
    guanosine nucleotide diphosphate dissociation inhibitor 1
    Primary source
    TAIR:AT2G44100
    Locus tag
    AT2G44100
    See related
    Araport:AT2G44100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AT-GDI1; ATGDI1; F6E13.23; F6E13.26; F6E13_26; guanosine nucleotide diphosphate dissociation inhibitor 1
    Summary
    GDP dissociation inhibitor involved in vesicular membrane traffic
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    Genomic context

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    See GDI1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Sequence:
    Chromosome: 2; NC_003071.7 (18241469..18245008)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ARGOS-like protein Neighboring gene Ankyrin repeat family protein Neighboring gene ncRNA Neighboring gene Seven transmembrane MLO family protein Neighboring gene Ribosomal protein L30/L7 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis gene isolated by a novel method for detecting genetic interaction in yeast encodes the GDP dissociation inhibitor of Ara4 GTPase. Ueda T, et al. Plant Cell, 1996 Nov. PMID 8953772, Free PMC Article
    2. At-GDI1 from Arabidopsis thaliana encodes a rab-specific GDP dissociation inhibitor that complements the sec19 mutation of Saccharomyces cerevisiae. Zárský V, et al. FEBS Lett, 1997 Feb 24. PMID 9091322
    3. Modes of interaction between the Arabidopsis Rab protein, Ara4, and its putative regulator molecules revealed by a yeast expression system. Ueda T, et al. Plant J, 2000 Feb. PMID 10758485
    4. CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells. Wu Y, et al. J Exp Bot, 2013 Aug. PMID 23846874, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084585.2
    NM_129973.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables Rab GDP-dissociation inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables Rab GDP-dissociation inhibitor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within plasma membrane to endosome transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    guanosine nucleotide diphosphate dissociation inhibitor 1
    NP_001078054.1
    • guanosine nucleotide diphosphate dissociation inhibitor 1 (GDI1); CONTAINS InterPro DOMAIN/s: Rab GTPase activator (InterPro:IPR002005), GDP dissociation inhibitor (InterPro:IPR018203), Rab GDI protein (InterPro:IPR000806); BEST Arabidopsis thaliana protein match is: RAB GDP dissociation inhibitor 2 (TAIR:AT3G59920.1); Has 1320 Blast hits to 1214 proteins in 252 species: Archae - 2; Bacteria - 0; Metazoa - 653; Fungi - 281; Plants - 182; Viruses - 0; Other Eukaryotes - 202 (source: NCBI BLink).
    NP_181938.1
    • guanosine nucleotide diphosphate dissociation inhibitor 1 (GDI1); CONTAINS InterPro DOMAIN/s: Rab GTPase activator (InterPro:IPR002005), GDP dissociation inhibitor (InterPro:IPR018203), Rab GDI protein (InterPro:IPR000806); BEST Arabidopsis thaliana protein match is: RAB GDP dissociation inhibitor 2 (TAIR:AT3G59920.1); Has 1316 Blast hits to 1209 proteins in 256 species: Archae - 2; Bacteria - 0; Metazoa - 652; Fungi - 289; Plants - 183; Viruses - 0; Other Eukaryotes - 190 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18241469..18245008
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129973.3 → NP_181938.1  guanosine nucleotide diphosphate dissociation inhibitor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181938.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DFX1, Q8LBY8, Q8VZB4, Q96254, Q96284
      UniProtKB/TrEMBL
      A0A178VSJ6, A0A5S9X753, A0A7G2EDK6
      Conserved Domains (1) summary
      cl21454
      Location:1 → 433
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_001084585.2 → NP_001078054.1  guanosine nucleotide diphosphate dissociation inhibitor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078054.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EDK6
      Conserved Domains (1) summary
      cl21454
      Location:1 → 430
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96254.1

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