U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    Gm45935 predicted gene, 45935 [ Mus musculus (house mouse) ]

    Gene ID: 107303348, updated on 17-Aug-2024

    Summary

    Official Symbol
    Gm45935provided by MGI
    Official Full Name
    predicted gene, 45935provided by MGI
    Primary source
    MGI:MGI:5825572
    See related
    AllianceGenome:MGI:5825572
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Setdb2-phf11c
    Summary
    This gene represents naturally-occurring readthrough transcription between the upstream Setdb2 (SET domain, bifurcated 2) gene to the downstream Phf11c (PHD finger protein 11C) gene. Some transcripts may also extend to the Phf11d (PHD finger protein 11D) gene. Readthrough transcripts may encode fusion proteins with similarity to proteins encoded by each of the individual genes. [provided by RefSeq, Mar 2016]
    Expression
    Ubiquitous expression in liver E14 (RPKM 2.5), thymus adult (RPKM 2.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gm45935 in Genome Data Viewer
    Location:
    14 C3; 14
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (59618282..59678329, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (59380833..59440880, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11570 Neighboring gene PHD finger protein 11B Neighboring gene STARR-seq mESC enhancer starr_36838 Neighboring gene STARR-seq mESC enhancer starr_36839 Neighboring gene PHD finger protein 11D Neighboring gene PHD finger protein 11C Neighboring gene SET domain, bifurcated 2 Neighboring gene STARR-positive B cell enhancer ABC_E4112 Neighboring gene calcium binding protein 39-like Neighboring gene cytidine and dCMP deaminase domain containing 1 Neighboring gene aldo-keto reductase family 1, member B8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General protein information

    Preferred Names
    Setdb2-Phf11c protein
    Names
    Setdb2-Phf11-1-Phf11-2 fusion
    Setdb2-Phf11c readthrough

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320725.1NP_001307654.1  Setdb2-Phf11c protein

      Status: VALIDATED

      Source sequence(s)
      AC114007
      UniProtKB/TrEMBL
      B4XVP6, B4XVP7
      Conserved Domains (4) summary
      smart00317
      Location:612674
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd01395
      Location:152212
      HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
      pfam05033
      Location:234346
      Pre-SET; Pre-SET motif
      cl22851
      Location:700813
      PHD_SF; PHD finger superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      59618282..59678329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)