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    Cd209f CD209f antigen [ Mus musculus (house mouse) ]

    Gene ID: 69142, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cd209fprovided by MGI
    Official Full Name
    CD209f antigenprovided by MGI
    Primary source
    MGI:MGI:1916392
    See related
    Ensembl:ENSMUSG00000051906 AllianceGenome:MGI:1916392
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SIGNR8; 1810029C22Rik
    Summary
    Enables D-mannose binding activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in mammary gland adult (RPKM 34.5), subcutaneous fat pad adult (RPKM 12.8) and 4 other tissues See more
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    Genomic context

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    See Cd209f in Genome Data Viewer
    Location:
    8 A1.1; 8 1.92 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (4152784..4155838, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (4102784..4105838, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 42 homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_20602 Neighboring gene STARR-seq mESC enhancer starr_20603 Neighboring gene axin interaction partner and dorsalization antagonist pseudogene Neighboring gene STARR-seq mESC enhancer starr_20605 Neighboring gene STARR-seq mESC enhancer starr_20606 Neighboring gene CD209g antigen Neighboring gene STARR-seq mESC enhancer starr_20608 Neighboring gene RIKEN cDNA 4932443L11 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:4162949-4163058 Neighboring gene STARR-positive B cell enhancer ABC_E355 Neighboring gene ecotropic viral integration site 5 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins. Powlesland AS, et al. J Biol Chem, 2006 Jul 21. PMID 16682406
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables D-mannose binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CD209f antigen

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026956.2 → NP_081232.2  CD209f antigen

      See identical proteins and their annotated locations for NP_081232.2

      Status: VALIDATED

      Source sequence(s)
      AK007638, BC099497
      Consensus CDS
      CCDS52472.1
      UniProtKB/TrEMBL
      G3UVT9, Q7TSU6
      Related
      ENSMUSP00000116355.2, ENSMUST00000145007.8
      Conserved Domains (1) summary
      cd03590
      Location:127 → 246
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      4152784..4155838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508867.2 → XP_006508930.1  CD209f antigen isoform X1

      UniProtKB/TrEMBL
      Q80ZY1
      Conserved Domains (1) summary
      cd03590
      Location:127 → 246
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

    2. XM_006508868.4 → XP_006508931.1  CD209f antigen isoform X2

      UniProtKB/TrEMBL
      Q8CHZ4
      Related
      ENSMUST00000207294.2
      Conserved Domains (1) summary
      cl02432
      Location:127 → 171
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    RNA

    1. XR_378666.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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