npr-32 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: npr-32
Official Full Name: G-protein coupled receptors family 1 profile domain-containing protein
Primary source: WormBase:WBGene00013782
Locus tag: CELE_Y116A8B.5
See related: AllianceGenome:WB:WBGene00013782
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in chemokine-mediated signaling pathway. Predicted to be located in membrane. Orthologous to human NPBWR1 (neuropeptides B and W receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See npr-32 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 12

Sequence:: Chromosome: IV; NC_003282.8 (17225969..17231058, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

we show that sensory neuron expression of the nape-1 gene, which encodes an enzyme synthesizing AEA, causes the regenerating motor axons to avoid sensory neurons and this avoidant response depends on NPR-19 and NPR-32. These results indicate that the navigation of regenerating axons is modulated by the action of AEA on NPR-19/32 GPCRs
Title: Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

Y116A8B.5 (e-PCR)
- UniSTS:320426

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: G-protein coupled receptors family 1 profile domain-containing protein

NP_503056.4

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

17225969..17231058 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070655.5 → NP_503056.4 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503056.4

Status: REVIEWED

UniProtKB/TrEMBL

O62403

Conserved Domains (1) summary

cd00637
Location:31 → 339

7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily