rpl-8 Large ribosomal subunit protein uL2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rpl-8
Official Full Name: Large ribosomal subunit protein uL2
Primary source: WormBase:WBGene00004413
Locus tag: CELE_B0250.1
See related: AllianceGenome:WB:WBGene00004413
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL8 (ribosomal protein L8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rpl-8 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 3

Sequence:: Chromosome: V; NC_003283.11 (20479689..20480834)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results indicate that C. elegans ribosomal protein genes are regulated by a complex novel series of regulatory elements that is evolutionarily distinct from those of all other species examined up until now
Title: Regulatory elements of Caenorhabditis elegans ribosomal protein genes.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0250.1 (e-PCR)
- UniSTS:317669

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables rRNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Large ribosomal subunit protein uL2

NP_507940.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

20479689..20480834

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_075539.9 → NP_507940.1 Large ribosomal subunit protein uL2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_507940.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9XVF7

Conserved Domains (3) summary

PTZ00180
Location:1 → 258

PTZ00180; 60S ribosomal protein L8; Provisional

pfam00181
Location:11 → 88

Ribosomal_L2; Ribosomal Proteins L2, RNA binding domain

pfam03947
Location:98 → 224

Ribosomal_L2_C; Ribosomal Proteins L2, C-terminal domain