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    cup-15 Coelomocyte uptake defective protein 15 [ Caenorhabditis elegans ]

    Gene ID: 174483, updated on 9-Dec-2024

    Summary

    Official Symbol
    cup-15
    Official Full Name
    Coelomocyte uptake defective protein 15
    Primary source
    WormBase:WBGene00009627
    Locus tag
    CELE_F42A8.3
    See related
    AllianceGenome:WB:WBGene00009627
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in lysosome organization. Predicted to be located in membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 5. Orthologous to human OSTM1 (osteoclastogenesis associated transmembrane protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cup-15 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (9353000..9354327)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Neighboring gene ncRNA Neighboring gene cGMP-dependent protein kinase interacting domain-containing protein Neighboring gene Doublecortin domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in lysosome organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Coelomocyte uptake defective protein 15
    NP_001379070.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9353000..9354327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393152.1NP_001379070.1  Coelomocyte uptake defective protein 15 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09322
      Conserved Domains (1) summary
      pfam09777
      Location:42290
      OSTMP1; Osteopetrosis-associated transmembrane protein 1 precursor