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    pgal-1 putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [ Caenorhabditis elegans ]

    Gene ID: 172108, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pgal-1
    Official Full Name
    putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1
    Primary source
    WormBase:WBGene00017671
    Locus tag
    CELE_F21F3.1
    See related
    AllianceGenome:WB:WBGene00017671
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity and peptidylamidoglycolate lyase activity. Predicted to be involved in peptide metabolic process. Predicted to be located in membrane. Predicted to be active in extracellular region. Is expressed in nervous system. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pgal-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (4906839..4911829)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein-S-isoprenylcysteine O-methyltransferase Neighboring gene Protein kinase domain-containing protein Neighboring gene DUF4149 domain-containing protein Neighboring gene Transmembrane protein 230 Neighboring gene Importin N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidylamidoglycolate lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in peptide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1
    NP_491475.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4906839..4911829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059074.8 → NP_491475.2  putative peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491475.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91268
      Conserved Domains (1) summary
      cd14958
      Location:59 → 344
      NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91268.2

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