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    sld-2 Ribosome biogenesis protein NOP53 [ Caenorhabditis elegans ]

    Gene ID: 188455, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sld-2
    Official Full Name
    Ribosome biogenesis protein NOP53
    Primary source
    WormBase:WBGene00020466
    Locus tag
    CELE_T12F5.1
    See related
    AllianceGenome:WB:WBGene00020466
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in several structures, including AB; EMS; Psub1; Psub2; and germ line. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sld-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (3741451..3742647)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase glh-4 Neighboring gene RING-type domain-containing protein Neighboring gene HTH La-type RNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene MATH (meprin-associated Traf homology) domain containing Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. Gaggioli V, et al. PLoS Genet, 2020 Dec. PMID 33320862, Free PMC Article
    2. CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans. Gaggioli V, et al. J Cell Biol, 2014 Feb 17. PMID 24535824, Free PMC Article
    3. DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans. Xia Y, et al. Science, 2023 Sep 22. PMID 37590372, Free PMC Article
    4. Domain selection combined with improved cloning strategy for high throughput expression of higher eukaryotic proteins. Chen Y, et al. BMC Biotechnol, 2007 Jul 30. PMID 17663785, Free PMC Article
    5. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans.
      Title: Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Ribosome biogenesis protein NOP53
    NP_491210.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3741451..3742647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058809.6 → NP_491210.1  Ribosome biogenesis protein NOP53 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491210.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44761
    Nucleotide Protein
    Heading Accession and Version

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