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    F44B9.5 Lipid droplet-regulating VLDL assembly factor AUP1 homolog [ Caenorhabditis elegans ]

    Gene ID: 176127, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F44B9.5
    Official Full Name
    Lipid droplet-regulating VLDL assembly factor AUP1 homolog
    Primary source
    WormBase:WBGene00018408
    Locus tag
    CELE_F44B9.5
    See related
    AllianceGenome:WB:WBGene00018408
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyltransferase activity and ubiquitin binding activity. Predicted to be involved in ERAD pathway. Predicted to be located in endoplasmic reticulum; lipid droplet; and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in vulA; vulB1; and vulB2. Orthologous to human AUP1 (AUP1 lipid droplet regulating VLDL assembly factor). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F44B9.5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (8013753..8016538, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative G-protein coupled receptor C06G4.5 Neighboring gene Uncharacterized protein Neighboring gene Cyclin-T1.1 Neighboring gene Cyclin-T1.2 Neighboring gene Protein lin-36 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipid droplet-regulating VLDL assembly factor AUP1 homolog
    NP_498746.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8013753..8016538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066345.8 → NP_498746.1  Lipid droplet-regulating VLDL assembly factor AUP1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498746.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34426
      Conserved Domains (2) summary
      smart00546
      Location:305 → 346
      CUE; Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs)
      cl17185
      Location:75 → 279
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34426.2

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