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    bus-5 NAD(P)-binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180525, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bus-5
    Official Full Name
    NAD(P)-binding domain-containing protein
    Primary source
    WormBase:WBGene00044621
    Locus tag
    CELE_F53B1.4
    See related
    AllianceGenome:WB:WBGene00044621
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in hypodermis; intestine; and rectum. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Orthologous to human TGDS (TDP-glucose 4,6-dehydratase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bus-5 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (2111397..2113104, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Conserved plasma membrane protein Neighboring gene Sphingomyelin synthase-related 1 Neighboring gene Metallo-beta-lactamase domain-containing protein 1 Neighboring gene Guanine nucleotide-binding protein alpha-5 subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems. Lanzerstorfer P, et al. Arch Toxicol, 2021 Feb. PMID 33159585, Free PMC Article
    2. Acquired stress resilience through bacteria-to-nematode interdomain horizontal gene transfer. Pandey T, et al. EMBO J, 2023 Dec 11. PMID 37953666, Free PMC Article
    3. The hmsHFRS operon of Xenorhabdus nematophila is required for biofilm attachment to Caenorhabditis elegans. Drace K, et al. Appl Environ Microbiol, 2008 Jul. PMID 18515487, Free PMC Article
    4. Caenorhabditis elegans mutants resistant to attachment of Yersinia biofilms. Darby C, et al. Genetics, 2007 May. PMID 17339204, Free PMC Article
    5. Multiple genes affect sensitivity of Caenorhabditis elegans to the bacterial pathogen Microbacterium nematophilum. Gravato-Nobre MJ, et al. Genetics, 2005 Nov. PMID 16079230, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dTDP-glucose 4,6-dehydratase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NAD(P)-binding domain-containing protein
    NP_508390.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2111397..2113104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075989.3 → NP_508390.1  NAD(P)-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508390.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20697
      Conserved Domains (1) summary
      cd05246
      Location:9 → 334
      dTDP_GD_SDR_e; dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs
    Nucleotide Protein
    Heading Accession and Version

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