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    atgp-1 Aamy domain-containing protein;alpha-glucosidase [ Caenorhabditis elegans ]

    Gene ID: 178504, updated on 9-Dec-2024

    Summary

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    Official Symbol
    atgp-1
    Official Full Name
    Aamy domain-containing protein;alpha-glucosidase
    Primary source
    WormBase:WBGene00000224
    Locus tag
    CELE_F26D10.9
    See related
    AllianceGenome:WB:WBGene00000224
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in carbohydrate metabolic process. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See atgp-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (17269342..17272181)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutamine synthetase Neighboring gene Lipoma HMGIC fusion partner-like 3 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters. Veljkovic E, et al. J Biol Chem, 2004 Feb 27. PMID 14668347
    2. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    3. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
    4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Aamy domain-containing protein;alpha-glucosidase
    NP_001367158.1
    • Confirmed by transcript evidence
    NP_503064.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17269342..17272181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070663.7 → NP_503064.2  alpha-glucosidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503064.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVU3
      Conserved Domains (2) summary
      pfam16028
      Location:43 → 100
      SLC3A2_N; Solute carrier family 3 member 2 N-terminus
      cl38930
      Location:97 → 512
      AmyAc_family; Alpha amylase catalytic domain family

    2. NM_001380570.1 → NP_001367158.1  Aamy domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2U2
      Conserved Domains (1) summary
      COG0366
      Location:12 → 122
      AmyA; Glycosidase [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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