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    kdin-1 KAP NTPase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178000, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kdin-1
    Official Full Name
    KAP NTPase domain-containing protein
    Primary source
    WormBase:WBGene00006490
    Locus tag
    CELE_F36H1.2
    See related
    AllianceGenome:WB:WBGene00006490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase regulator activity. Predicted to be involved in nerve growth factor signaling pathway. Predicted to be located in membrane. Is expressed in several structures, including excretory cell; intestine; nervous system; non-striated muscle; and pharynx. Orthologous to human KIDINS220 (kinase D interacting substrate 220). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kdin-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    26
    Sequence:
    Chromosome: IV; NC_003282.8 (11038655..11047422)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene peptidylprolyl isomerase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Tyrosine-protein phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans. Li Q, et al. Elife, 2020 Nov 24. PMID 33228848, Free PMC Article
    2. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nerve growth factor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    KAP NTPase domain-containing protein
    NP_001040942.3
    • Confirmed by transcript evidence
    NP_001040943.3
    • Confirmed by transcript evidence
    NP_001076687.3
    • Confirmed by transcript evidence
    NP_001294014.1
    • Confirmed by transcript evidence
    NP_001294015.1
    • Confirmed by transcript evidence
    NP_001294016.1
    • Confirmed by transcript evidence
    NP_001294017.1
    • Confirmed by transcript evidence
    NP_001294018.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11038655..11047422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047477.7 → NP_001040942.3  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040942.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20109
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 973
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    2. NM_001047478.6 → NP_001040943.3  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040943.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q27GQ4
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 973
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    3. NM_001083218.6 → NP_001076687.3  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001076687.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q067Y1
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 1002
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    4. NM_001307087.3 → NP_001294016.1  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294016.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AD39
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 1002
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    5. NM_001307089.3 → NP_001294018.1  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294018.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AL87
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 976
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    6. NM_001307086.3 → NP_001294015.1  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294015.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AEC1
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 1005
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    7. NM_001307085.3 → NP_001294014.1  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294014.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AD72
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 1005
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)

    8. NM_001307088.3 → NP_001294017.1  KAP NTPase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294017.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AJK4
      Conserved Domains (4) summary
      PHA02874
      Location:66 → 370
      PHA02874; ankyrin repeat protein; Provisional
      pfam07693
      Location:464 → 976
      KAP_NTPase; KAP family P-loop domain
      sd00045
      Location:95 → 126
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:332 → 419
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
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