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    set-5 SET domain-containing protein;SPK domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179973, updated on 9-Dec-2024

    Summary

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    Official Symbol
    set-5
    Official Full Name
    SET domain-containing protein;SPK domain-containing protein
    Primary source
    WormBase:WBGene00008145
    Locus tag
    CELE_C47E8.8
    See related
    AllianceGenome:WB:WBGene00008145
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in germ line. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See set-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    18
    Sequence:
    Chromosome: V; NC_003283.11 (14698966..14707601)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Protein unc-112 Neighboring gene Uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
    2. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190
    3. Epigenetics in C. elegans: facts and challenges. Wenzel D, et al. Genesis, 2011 Aug. PMID 21538806
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    SET domain-containing protein;SPK domain-containing protein
    NP_001256612.1
    • Confirmed by transcript evidence
    NP_001256613.1
    • Confirmed by transcript evidence
    NP_001256614.1
    • Confirmed by transcript evidence
    NP_001263889.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14698966..14707601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269683.3 → NP_001256612.1  SET domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256612.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEE4
      Conserved Domains (4) summary
      PHA03309
      Location:793 → 1008
      PHA03309; transcriptional regulator ICP4; Provisional
      smart00317
      Location:36 → 151
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00583
      Location:1006 → 1118
      SPK; domain in SET and PHD domain containing proteins and protein kinases
      PTZ00108
      Location:1115 → 1328
      PTZ00108; DNA topoisomerase 2-like protein; Provisional

    2. NM_001276960.4 → NP_001263889.1  SET domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263889.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ESG9
      Conserved Domains (4) summary
      PHA03309
      Location:793 → 1008
      PHA03309; transcriptional regulator ICP4; Provisional
      smart00317
      Location:36 → 151
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00583
      Location:1006 → 1118
      SPK; domain in SET and PHD domain containing proteins and protein kinases
      PTZ00108
      Location:1115 → 1330
      PTZ00108; DNA topoisomerase 2-like protein; Provisional

    3. NM_001269684.3 → NP_001256613.1  SPK domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256613.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLH7
      Conserved Domains (3) summary
      PHA03309
      Location:565 → 780
      PHA03309; transcriptional regulator ICP4; Provisional
      smart00583
      Location:778 → 890
      SPK; domain in SET and PHD domain containing proteins and protein kinases
      PTZ00108
      Location:887 → 1103
      PTZ00108; DNA topoisomerase 2-like protein; Provisional

    4. NM_001269685.3 → NP_001256614.1  SPK domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256614.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLH6
      Conserved Domains (3) summary
      PHA03309
      Location:565 → 780
      PHA03309; transcriptional regulator ICP4; Provisional
      smart00583
      Location:778 → 890
      SPK; domain in SET and PHD domain containing proteins and protein kinases
      PTZ00108
      Location:887 → 1100
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
    Nucleotide Protein
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