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    B0280.9 U3 small nucleolar RNA-associated protein 18 homolog [ Caenorhabditis elegans ]

    Gene ID: 175994, updated on 9-Dec-2024

    Summary

    Official Symbol
    B0280.9
    Official Full Name
    U3 small nucleolar RNA-associated protein 18 homolog
    Primary source
    WormBase:WBGene00015104
    Locus tag
    CELE_B0280.9
    See related
    AllianceGenome:WB:WBGene00015104
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Orthologous to human UTP18 (UTP18 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See B0280.9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (7120905..7122895, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Nuclear hormone receptor family member nhr-10 Neighboring gene Probable-ribose 5-phosphate isomerase Neighboring gene Uncharacterized protein

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in rRNA processing  
    Component Evidence Code Pubs
    part_of Pwp2p-containing subcomplex of 90S preribosome  
    located_in nucleolus  
    located_in nucleus  
    part_of small-subunit processome  

    General protein information

    Preferred Names
    U3 small nucleolar RNA-associated protein 18 homolog
    NP_498555.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7120905..7122895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066154.6 → NP_498555.1  U3 small nucleolar RNA-associated protein 18 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498555.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42000
      Conserved Domains (3) summary
      COG2319
      Location:66 → 424
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:258 → 296
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:167 → 423
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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