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    Y69H2.3 Follistatin-like domain-containing protein;TIL domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180221, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y69H2.3
    Official Full Name
    Follistatin-like domain-containing protein;TIL domain-containing protein
    Primary source
    WormBase:WBGene00013481
    Locus tag
    CELE_Y69H2.3
    See related
    AllianceGenome:WB:WBGene00013481
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y69H2.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    24
    Sequence:
    Chromosome: V; NC_003283.11 (18656088..18664126, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene TIL domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
    2. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Duchaine TF, et al. Cell, 2006 Jan 27. PMID 16439208
    3. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
    4. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    5. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Follistatin-like domain-containing protein;TIL domain-containing protein
    NP_001123062.1
    • Confirmed by transcript evidence
    NP_001263926.1
    • Confirmed by transcript evidence
    NP_001263927.1
    • Confirmed by transcript evidence
    NP_001263928.1
    • Confirmed by transcript evidence
    NP_001360619.1
    • Confirmed by transcript evidence
    NP_001360620.1
    • Confirmed by transcript evidence
    NP_507642.2
    • Confirmed by transcript evidence
    NP_507643.3
    • Confirmed by transcript evidence
    NP_507644.2
    • Confirmed by transcript evidence
    NP_507645.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      18656088..18664126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075243.8 → NP_507644.2  TIL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507644.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1T5
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    2. NM_001373189.3 → NP_001360619.1  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IMV3
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    3. NM_001373188.2 → NP_001360620.1  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V6M3C6
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    4. NM_075241.8 → NP_507642.2  TIL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507642.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I4B9
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    5. NM_001129590.4 → NP_001123062.1  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123062.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8WI97
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    6. NM_075242.6 → NP_507643.3  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507643.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1T6
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    7. NM_001276998.3 → NP_001263927.1  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263927.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8EC36
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    8. NM_075244.8 → NP_507645.2  TIL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507645.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I4B8
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    9. NM_001276999.4 → NP_001263928.1  Follistatin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263928.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E6L7
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    10. NM_001276997.4 → NP_001263926.1  TIL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263926.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E811
      Conserved Domains (1) summary
      pfam01826
      Location:26 → 80
      TIL; Trypsin Inhibitor like cysteine rich domain

    RNA

    1. NR_023988.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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