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    T27A3.5 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

    Gene ID: 188965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T27A3.5
    Official Full Name
    Protein-tyrosine phosphatase
    Primary source
    WormBase:WBGene00020841
    Locus tag
    CELE_T27A3.5
    See related
    AllianceGenome:WB:WBGene00020841
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Orthologous to human PTPN7 (protein tyrosine phosphatase non-receptor type 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T27A3.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (6100261..6101789, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SPerm CHromatin enriched Neighboring gene ncRNA Neighboring gene Sperm-specific class P protein 16 Neighboring gene NADH dehydrogenase subunit 4L;Ovule protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase
    NP_491761.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6100261..6101789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059360.4 → NP_491761.3  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491761.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91498
      Conserved Domains (2) summary
      smart00194
      Location:73 → 326
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:100 → 326
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein
    Heading Accession and Version

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