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    ZK856.5 Metallophos domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191439, updated on 9-Dec-2024

    Summary

    Official Symbol
    ZK856.5
    Official Full Name
    Metallophos domain-containing protein
    Primary source
    WormBase:WBGene00014106
    Locus tag
    CELE_ZK856.5
    See related
    AllianceGenome:WB:WBGene00014106
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including SMPDL3B (sphingomyelin phosphodiesterase acid like 3B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ZK856.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (10186011..10190131, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Saposin B-type domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene NGF domain-containing protein Neighboring gene Secreted protein Neighboring gene EF-hand domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Metallophos domain-containing protein
    NP_001369926.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10186011..10190131 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383382.2NP_001369926.1  Metallophos domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23640
      Conserved Domains (1) summary
      cd00842
      Location:23325
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain