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    C06C3.3 Doublecortin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182302, updated on 9-Dec-2024

    Summary

    Official Symbol
    C06C3.3
    Official Full Name
    Doublecortin domain-containing protein
    Primary source
    WormBase:WBGene00007374
    Locus tag
    CELE_C06C3.3
    See related
    AllianceGenome:WB:WBGene00007374
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in intracellular signal transduction. Predicted to be active in microtubule and microtubule organizing center. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Orthologous to human DCDC2 (doublecortin domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See C06C3.3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (9369074..9372493, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Coelomocyte uptake defective protein 15 Neighboring gene ncRNA Neighboring gene cGMP-dependent protein kinase interacting domain-containing protein Neighboring gene Secreted protein Neighboring gene FBD domain-containing protein Neighboring gene Secreted protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Doublecortin domain-containing protein
    NP_495995.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9369074..9372493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063594.4NP_495995.2  Doublecortin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495995.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17711
      Conserved Domains (2) summary
      PTZ00121
      Location:194556
      PTZ00121; MAEBL; Provisional
      smart00537
      Location:1398
      DCX; Domain in the Doublecortin (DCX) gene product