U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nemp-1 Nuclear envelope integral membrane protein [ Caenorhabditis elegans ]

    Gene ID: 175204, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nemp-1
    Official Full Name
    Nuclear envelope integral membrane protein
    Primary source
    WormBase:WBGene00017328
    Locus tag
    CELE_F10C5.2
    See related
    AllianceGenome:WB:WBGene00017328
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nuclear inner membrane. Predicted to be active in nuclear envelope. Is expressed in several structures, including arcade cell; pharyngeal cell; pharyngeal-intestinal valve; rectal gland cell; and spermatheca. Orthologous to human NEMP1 (nuclear envelope integral membrane protein 1) and NEMP2 (nuclear envelope integral membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See nemp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (472317..475349)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene MAGUK family Neighboring gene Cell division cycle protein 23 homolog Neighboring gene Ovule protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nuclear lipid droplets and nuclear damage in Caenorhabditis elegans. Mosquera JV, et al. PLoS Genet, 2021 Jun. PMID 34133414, Free PMC Article
    2. The NEMP family supports metazoan fertility and nuclear envelope stiffness. Tsatskis Y, et al. Sci Adv, 2020 Aug. PMID 32923640, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Nuclear envelope integral membrane protein
    NP_497202.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      472317..475349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064801.9 → NP_497202.2  Nuclear envelope integral membrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497202.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19293
      Conserved Domains (1) summary
      pfam10225
      Location:127 → 378
      DUF2215; Uncharacterized conserved protein (DUF2215)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19293.3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools